CPA #3 Questions Flashcards

(32 cards)

1
Q

define pathogenicity

A

the ability of a microbe to cause disease

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2
Q

define virulence

A

the degree of pathogenicity; relative ability of a pathogen to infect a host; indicates severity of disease

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3
Q

define phagocytosis

A

digestion via phagocyte; engulf and remove pathogens from the body

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4
Q

are antiphagocytic factors good for the body?

A

bad; they interrupt the body’s phagocytic cells, stopping them from removing pathogens

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5
Q

how are capsules antiphagocytic?

A

slippery due to the mycolic acid coating on outside; the capsules are composed of chemicals found in the human body; therefore they do not trigger the immune response

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6
Q

what are the 5 stages of the disease process in order?

A
  1. incubation
  2. prodromal
  3. illness
  4. decline
  5. convalescence
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7
Q

which stage of the disease process does not always present with every disease?

A

prodromal

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8
Q

define incubation period

A

first stage; no signs of symptoms, time between infection and first s/s

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9
Q

define prodromal stage

A

second stage; vague, general s/s

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10
Q

define illness stage

A

third stage; most severe s/s; usually when the physician first sees a patient

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11
Q

define decline stage

A

declining s/s

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12
Q

define convalescence stage

A

no s/s at all

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13
Q

define incidence

A

number of new cases of a disease in a given area of population during a given period of time

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14
Q

define prevalence

A

total number of cases, both new and already existing in a given area of population during a given period of time

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15
Q

where do hospitals report infectious disease occurances?

A

local health department

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16
Q

what federal agency do infectious disease occurrences have to be reported to?

A

Centers for Disease Control and Prevention (CDC)

17
Q

what is the MMWR?

A

morbidity and mortality weekly report; to be able to push the information out to the public

18
Q

when and where did the outbreak of botulism occur in Ohio?

A

April 21, 2015 in Fairfield County OH

19
Q

how many cases of botulism were identified before reporting to CDC? Why?

A

only 1; a single case can signal an outbreak

20
Q

what did all of the patients have in common?

A

attended a church potluck

21
Q

what did the CDC do in response to learning of this outbreak?

A

investigation of cause

22
Q

how many consumed potluck food? how many were confirmed cases? how many dies?

A

77 people consumed; 25 people were confirmed; 1 person died

23
Q

how many patients received botulinum antitoxin? how many received endotracheal intubation or mechanical ventilation?

A

25 received antitoxin; 11 required intubation/ventilation

24
Q

how many patients were discharged within 1 week? how many lab confirmed cases were there?

A

16 discharged; 19 lab confirmed

25
what does it mean to be lab confirmed?
stool/ specimen samples positive for botulism neurotoxin type A or Clostridium botulism type A
26
what steps did CDC take to determine cause of outbreak?
interviewed patients and gathered discarded food samples
27
what was the source of the outbreak?
improperly canned homemade potato salad
28
what does the CDC recommend to avoid this situation?
pressure canning, not water canning. boiling water canning does not kill the spores.
29
why is the CNS described as axenic?
no openings allow microbial colonization; it has no normal microbiota
30
how do pathogens access the CNS?
breaks in bones/ meninges (medical procedures); microbes carried in the blood/lymph can penetrate blood/brain barrier
31
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