Flashcards in CV development and defects wk2 Deck (32):
1
Heart develops from __________ mesoderm.
splanchnic
2
5 components of the early developing heart tube:
1. truncus arteriosus
2. bulbus cordis
3. ventricle
4. atrium
5. sinus venosus
3
__________ septum forms the foramen ovale, ___________ septum forms the valve associated with the FO.
Secondary
Primary
4
Bulbar and truncal ridge tissues (from neural crest mesenchyme) give rise to?
aorticopulmonary septum
5
Three parts of the interventricular septum:
1. muscular from myoblasts
2. membranous -- endocardial cushions + aorticopulmonary septum
6
Aortic sac contributes to?
aortic arch
brachiocephalic trunk
7
Left 4th aortic arch --> ?
aortic arch
8
Right 4th aortic arch --> ?
right subclavian artery
9
Left 6th aortic arch (proximal)--> ?
proximal left pulmonary artery
10
Left 6th aortic arch (distal) --> ?
ductus arteriosus --> ligamentum arteriosum (after birth)
11
Right 6th aortic arch (proximal) --> ?
proximal right pulmonary artery
12
Right 6th aortic arch (distal) --> ?
degenerates
13
Umbilical vein --> ?
hepatic ligamentum teres (round ligament of the liver)
14
Ductus venosum --> ?
ligamentum venosum
15
Umbilical arteries (distal)--> ?
medial umbilical ligaments
16
Umbilical arteries (proximal) --> ?
superior vesical arteries (supply urinary bladder)
17
Left to right shunts - cyanosis several months to years after birth "blue kids":
1. atrial septal defect
2. ventricular septal defect
3. Patent ductus arteriosus
18
Right to left shunts, cyanosis early in postnatal life "blue babies":
1. Tetralogy of Falllot
2. Transposition of the Great arteries
3. Truncus arteriosus
19
Excessive resorption of the primary septum
or
incompetent foramen ovale due to hypoplastic growth of secondary septum
Atrial septal defect
20
Most common congenital heart abnormality:
Ventricular septal defect
**90% involve membranous portion
21
Associated with maternal rubella:
Patent ductus arteriosus
22
"Machinery-like" murmur...
patent ductus arteriosus
23
4 defects in Tetralogy of Fallot:
1. Ventricular septal defect
2. pulmonary stenosis
3. overriding (large) aorta
4. right ventricular hypertrophy
24
Malformation common in type 1 DM mother:
Transposition of the Great Arteries
25
common aorticopulmonary outlet receives blood from both ventricles
due to failure of bulbar and truncal ridges to develop
Truncus arteriosus
26
asymmetrical division or spiraling of the aorticopulmonary septum
aortic or pulmonary stenosis and atresia
27
BP higher in upper extremities
postductal coartation of the aorta
28
patent ductus arteriosus and cyanosis in LE
preductal coarctation of the aorta
29
PDA
pulm stenosis
vent septal defect
maternal rubella
30
deletion of 22q11
Tetralogy of Fallot
Truncus arteriosus
DiGeorge syndrome
31
CV abnormalities associated with trisomy 21
atrial septal defect
ventricular septal defect
32