CV development and defects wk2 Flashcards Preview

CRRAB 1 > CV development and defects wk2 > Flashcards

Flashcards in CV development and defects wk2 Deck (32):
1

Heart develops from __________ mesoderm.

splanchnic

2

5 components of the early developing heart tube:

1. truncus arteriosus

2. bulbus cordis

3. ventricle

4. atrium

5. sinus venosus

3

__________ septum forms the foramen ovale, ___________ septum forms the valve associated with the FO.

Secondary

Primary

4

Bulbar and truncal ridge tissues (from neural crest mesenchyme) give rise to?

aorticopulmonary septum

5

Three parts of the interventricular septum:

1. muscular from myoblasts

2. membranous -- endocardial cushions + aorticopulmonary septum

6

Aortic sac contributes to?

aortic arch

brachiocephalic trunk

7

Left 4th aortic arch --> ?

aortic arch

8

Right 4th aortic arch --> ?

right subclavian artery

9

Left 6th aortic arch (proximal)--> ?

proximal left pulmonary artery

10

Left 6th aortic arch (distal) --> ?

ductus arteriosus --> ligamentum arteriosum (after birth)

11

Right 6th aortic arch (proximal) --> ?

proximal right pulmonary artery

12

Right 6th aortic arch (distal) --> ?

degenerates

13

Umbilical vein --> ?

hepatic ligamentum teres (round ligament of the liver)

14

Ductus venosum --> ?

ligamentum venosum

15

Umbilical arteries (distal)--> ?

medial umbilical ligaments

16

Umbilical arteries (proximal) --> ?

superior vesical arteries (supply urinary bladder)

17

Left to right shunts - cyanosis several months to years after birth "blue kids":

1. atrial septal defect

2. ventricular septal defect

3. Patent ductus arteriosus

18

Right to left shunts, cyanosis early in postnatal life "blue babies":

1. Tetralogy of Falllot

2. Transposition of the Great arteries

3. Truncus arteriosus

19

Excessive resorption of the primary septum

or

incompetent foramen ovale due to hypoplastic growth of secondary septum

Atrial septal defect

20

Most common congenital heart abnormality:

Ventricular septal defect

**90% involve membranous portion

21

Associated with maternal rubella:

Patent ductus arteriosus

22

"Machinery-like" murmur...

patent ductus arteriosus

23

4 defects in Tetralogy of Fallot:

1. Ventricular septal defect

2. pulmonary stenosis

3. overriding (large) aorta

4. right ventricular hypertrophy

24

Malformation common in type 1 DM mother:

Transposition of the Great Arteries

25

common aorticopulmonary outlet receives blood from both ventricles

due to failure of bulbar and truncal ridges to develop

Truncus arteriosus

26

asymmetrical division or spiraling of the aorticopulmonary septum

aortic or pulmonary stenosis and atresia

27

BP higher in upper extremities

postductal coartation of the aorta

28

patent ductus arteriosus and cyanosis in LE

preductal coarctation of the aorta

29

PDA
pulm stenosis
vent septal defect

maternal rubella

30

deletion of 22q11
Tetralogy of Fallot
Truncus arteriosus

DiGeorge syndrome

31

CV abnormalities associated with trisomy 21

atrial septal defect

ventricular septal defect

32

15q21.1
5q23.31
FBN1 gene
fibrillin-1 glycoprotein abnormality

Aortic stenosis

Marfan syndrome