Flashcards in cyclic lipopeptide Deck (10):
what is the only agent
what is the mechanism of action
insertion into the gram (+) cell membrane causing depolarization and ultimately ddeath
MRSA, MSSA, coagulase negative staph, enterococcus (VRE), streptococci.
does this work against gram -
does this work against anaerobes
what are the uses for this
alternative to vancomycin, VRE infection
what are the adverse effects
myalgias, rhabdomyolysis, eosinophilic pneumonia
is there resistance?
yes, but rare.
is this effective for pulmonary infections
no. surfactant inactivates it.