oxazolidinones Flashcards

1
Q

mechansm

A

bind to 23s rRNA of the 50s subunit

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2
Q

spectrum

A

gram (+) MRSA, VRE, coagul (-), strep.

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3
Q

is there resistance

A

rare

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4
Q

place in tehrapy

A

VRE

alternative to vancomycin

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5
Q

when do we avoid using these

A

bactermia/endocarditis

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6
Q

SE

A

bone marrow suppression after 2 wks.

periopheral neuropathy

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7
Q

drug interactiosn

A

MOAi possible serotonin syndrome

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