Disorder Of Primary And Platelet Flashcards

(48 cards)

1
Q

Hemorrhage of blood ino areas of skin, mucous membranes and other tissue

A

Purpura

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2
Q

Form of purpura in which blood escape inti large areas of skin and mucous membrane but into deep tissues

A

Ecchymosis

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3
Q

Nosebleed

A

Epistaxis

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4
Q

Leakage of blood into join cavities

A

Hemarthrosis

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5
Q

Vomits of blood

A

Hematemesis

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6
Q

Swelling or tumor in the tissues or a body cavities that contains clotted blood

A

Hematoma

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7
Q

Hemoglobin in the urine

A

Hemoglobinuria

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8
Q

Stool containing dark or black blood

A

Melena

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9
Q

Excessive menstrual bleeding

A

Menorrhagia

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10
Q

Present of urea in urine

A

Uremia

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11
Q

Disorder of primary hemostasis

A

Vascular disorder

Platelet disorder

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12
Q

Purplish red pinpoint hemorrhagic spots in the skin caused by loss of capillary ability to withstand nomal blood pressure and trauma

A

Petechiae

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13
Q

Other name for hereditary hemorrhagic telangiectasia

A

Osler weber rendu disease

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14
Q

Other name for congenital hemangiomata

A

Kasaback merritt syndrome

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15
Q

Condition of increase bascular fragility

A

Ehlers Danlos syndrome

Marfan’s syndrome

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16
Q

Tumor composed of blood vessel

A

Congenital hemangiomata

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17
Q

Most common inherited vascular disorder the blood vessel walls are thin and lacks smooth muscle

A

Hereditary hemorrhagic telangiectasia

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18
Q

Elastic fiber in small arteries are calcified and structurely abnormal

A

Pseudoxanthoma elasticum

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19
Q

Degradation of collagen and elastin

A

Senile purpura

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20
Q

Deficiency of vitamin C/ascorbic acid

21
Q

Immunilogic damage to endothelial cell

A

Henoch schonlein purpura

22
Q

What ere the 3 hereditary qualitative platelet disorder

A

Platelet adhesion
Platelet aggregation
Platlet secretion/storage pool defect

23
Q

What are the diorder under platelet aggregation

A

Glanzmann’s thrombasthenia

24
Q

Qualitative disirder of platelet secretion/storage pool defect

A

Gray platelet
Hermansky pudlak
Wiskott aldrich
Chediak higaski

25
Qualitative hereditary disorder for platelet adhesion
vWD | Bernard soulier
26
Abnormal in vWD
Ristocetin
27
Lack of vwf fro normak platelet adhesion
vWD
28
Platelet aggregation test for vwd
Normal platelet aggregation test with epinephrine collagen ADP
29
Def gp1b (receptor for vwf) giant platelet syndrome
Bernard soulier
30
Platelet aggregation test for bernard soulier
Normal platelet aggregation with ECA
31
Abnormal in bernard soulier
Ristocetin
32
What are the acquired qualitative disorder
``` Uremia Paraproteinemias Acute myeloblastic leukemia Myeloproliferative disorder Drugs ```
33
Abrnormal protein condition characterized by coating of platelet membrane with abnormal protein
Paraproteinemias
34
Condition is characterized by the presence of abnormal megakaryocyte
Acute myeloid leukemia
35
Needed for normal plateleet aggregation
Fribrinogen
36
Def in gpllb-llla conplex
Glanzmann's thrombasthenia
37
Ph receptor fro fibrinogen
Gpllb-llla complex
38
Platelet aggregation test for glanzmann's thrombasthenia
Normal platelet aggregatio with ristocetin
39
Abnormal of glanzmann's thrombasthenia
ECA
40
Decrease b, production
Thrombocytopenia
41
Quantitative disorsers
Thrombocytosis | Thrombocytopenia
42
Example of dilusion loss of plt ct
Mass blood transfusion
43
Example of increase pltls squestion of spleen
Splenomegaly
44
Example of due to dec of bm activity
Aplastic anemia | Pancytopenia
45
Example of dec survival time
DIC | inc ITP destruction
46
Auto ab for platelets
Immune thrombocytopenic purpura
47
Mass consumption of platelets
Disseminated intravascular coagulation
48
Dec in all froms of blood cells plt wbc, rbc
Pacytopenia