Plaelet Studies Flashcards

1
Q

Increase in platelet ass with disease

A

Thrombocytopenia

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2
Q

Increase platelet ct but without disease

A

Thrombocythemia

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3
Q

Nv of platelet

A

200-400,000/mm3

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4
Q

Factors with in increase platelet ct

A

Polycythemia vera
After splenectomy
Thrombocythemia
Among with tb

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5
Q

Factors with decrease in platelet ct

A
Pernicious anemia
Aplastic anemia
Lesion involving MB
Acute leukemia
Idiopathic
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6
Q

Method called in light microscopy

A

Rees and ecjker

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7
Q

Rees and ecker is made up of

A

Brilliant cresyl blue, na citrate, water

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8
Q

2nd light microscopy in method

A

Guy and leake’s method

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9
Q

Diluting fluid of 2nd lightmicroscopy

A

Crystal violet, na citrate and water

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10
Q

Formula of 1st light microscopy

A

Ply counter x 10 x 200 / 4

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11
Q

Formula of 2!nd light microscopy

A

Platelet counter x 10 x 200 x 1

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12
Q

Method under phase microscopy

A
Brencher cronkite
Unopette 
Nygard's
Van allen
Tocantin's
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13
Q

Most accurate method in phase microscopu

A

Brecher cronkite

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14
Q

What diluting fluid used in phase microscopy

A

1% nh4 c204

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15
Q

Nv in phase microscopy

A

150,000-450,000/mm3

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16
Q

Nv in light microscopy

A

140,000-340,000/mm3

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17
Q

Life span of platelet

A

8-11 days

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18
Q

What are the 2 indirect method

A

Damashek

Fonio

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19
Q

Dikuting fluid of damashek’s method

A

Brilliant cresyl blue, na citrate, dw, sucrose, formalin

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20
Q

Nv of damashek

A

500-900,000

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21
Q

Diluting fluid of fonio

A

14% mg2sO4

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22
Q

Counted by means of electronic particle counter

A

Semi automated

23
Q

Counted by means of eptical particle under the principle of dark field microscopy or electronic particle aperture

A

Fully automated

24
Q

Solidifying of blood brought about by different coagulation factors. Esp when the blood is taken out from the body

A

Coagulation

25
Entire mechanism by which bleeding from an injured blood vessel is spontaneously controlled and stop
Hemostasis
26
3 general method in coagulation of hemostasis
Bleeding time Clotting time Clot retraction time
27
Nv of dukes method
2-4mins
28
Nv of ivys method
1-7mins
29
Puncturing decvuce of ivys method
Bard parker blade, sohygmanometer in 40mmhg
30
Uses pre warmed NSS with 37 def temp, dip puncture finger until bleeding stops
Copley la litch method
31
Nv of copley la litch
3-6mins
32
Patient should abstain taking aspirin in 3 days
Aspirin tolerance test
33
If more than 6mins of bt in aspirin tolerance
Do not proceed
34
Do the dukes method for bt in what method
Aspirin tolerance test
35
Nv of aspirin tolerance test
Difference bet 1st and 2nd should not exceed than 2mins
36
It test the ability of the capillary under inc hypoxia and hydrostatic pressure
Capillary fragility test
37
Observe of the presence of petechiae
Capillary fragility test
38
Get the mid value of of the pt systolic and diastolic pressure, retain those within 5mins and wait for presence of petechia
Rumple leede test
39
Nv of petechiometer
0-2
40
The pressure is 200nm
Suction or petechiometer
41
Time it takes for a fluid blood to solidify after it has been taken out of the body
Coagulation time
42
Methods under coagulation time
``` Slide method Capillary tube method Lee and white method Prothrombin time Partial thromboplastin time ```
43
Put a drop of blood and fist put every 30 sec, obserbe for fibri trends then stop
Slide method
44
Nv of capillary tube method under sabraze
3-7mins
45
Nv of slide method
2-4mins
46
Uses ordinary capillary tube blue
Dale and laidlaw
47
Uses special capillary tube which has wider diameter
Sabraze
48
Whole blood clotting time Prepare 3 test tube 1ml blood each tube Tilt every 39secs
Lee and white method
49
Nv of lee and white method
7-15mins
50
Use of measure the extrinsic coagulation system and determine coagulation factor 2,5,7,10
Prothrombin time
51
Prothrombine time uses
Citrate plasma
52
Nv of prothrombin time
10-12 secs
53
Measure intrinsic coagulation system ans will measure deficiency of coag factors 8,9,12,11
Partial thromboplastin