DMD - L1 Flashcards Preview

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Flashcards in DMD - L1 Deck (12):
1

Topics?

Muscle structure
Muscle function
Metabolism
Types of muscle fibre

2

Describe the structure of muscle

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3

Describe the structure of sarcomeres

HIMAZ

4

Explain the sliding filament theory

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5

Explain the cross-bridge cycle

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6

What is dystrophin?

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7

Where can ATP be obtained from?

within the fibre
creatine phosphate
glucose in the cell (as glycogen)
glucose & fatty acids from blood

8

Describe aerobic and anaerobic respiration

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9

Describe the energy source graph

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10

Type I muscle fibres?

red fibres, slow oxidative, slow twitch, fatigue resistant
contain:
large amount of myoglobin, many mitochondria
many blood capillaries
generate A TP aerobically (oxidative)
split ATP at a slow rate
slow contraction velocity, resistant to fatigue
found in large numbers in postural muscles
needed for aerobic activities like long distance running

11

Type IIA muscle fibres?

red fibres, fast oxidative, fast twitch, fatigue resistant
contain:
large amount of myoglobin, many mitochondria, many capillaries
high capacity for generating ATP by oxidation. Split ATP at a very rapid rate, hence, high contraction velocity o resistant to fatigue but not as much as slow oxidative fibres
needed for middle distance running and swimming

12

Type IIB muscle fibres?

white fibres, fast glycolytic, fast twitch
• contain:
o low myoglobin content, few mitochondria, few capillaries
o large amount of glycogen, split ATP very quickly, anaerobic glycolysis o fatigue easily
o needed for explosive sports like sprinting