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Flashcards in DMD - L3 Deck (8)
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1

Topics?

DMD
statistics
clinical presentations
diagnosis
disease progression
complications
BMD
statistics
disease progression

2

DMD statistics?

onset

3

DMD clinical presentations? (7)

delayed motor milestones (walking >18 months)
gait difficulties (proximal, Gower's manoeuvre)
enlarged, rubbery muscles
weak neck flexors
lumbar lordosis
fatigability
speech delay, learning problems

4

DMD diagnosis?

serum creatine kinase (normal

5

DMD disease progression?

3-6 years
8 years
10-13 years
teen-early 20s

6

DMD complications? (6) Explain each one

respiratory deficit
sleep-disordered breathing
cardiac involvement
orthopaedic involvement
CNS involvement
cognitive issues

7

BMD statistics?

onset >5 years
incidence 1/35,000 male births
clinical onset variable
wheelchair dependency >16yrs

8

BMD disease progression?

-