drug names-1 Flashcards by Angelica J

botulinum toxin

blocks ACh release from vesicles

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carbachol

choline ester

nicotinic muscarinic

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bethanechole

choline ester muscarinic

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oxotremorine

muscarinic agonist

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pilocarpine

muscarinic agonist

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edrophonium

anticholinesterase
simple alchohol
reversible theraputic

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neostigmine

anticholinesterase
ester with ammonium
reversible theraputic

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malathion

anticholinesterase
organophosphatase
insecticide

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soman

anticholinesterase
organophosphatase
nerve gas

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succinylcholine

nicotinic antagonist (neuromuscular blocker)
paralysis during surgery

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D-Tubocurarine

nicotinic antagonist (neuromuscular blocker)
poison darts

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α-bungarotoxin

nicotinic antagonist (neuromuscular blocker)
protein in snake venom

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atropine

muscarinic antagonist

dilate pupils

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scopalamine

muscarinic antagonist

motion sickness

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ipratropium

muscarinic antagonist

COPD

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isoproterenol

β agonist
(ANI & IAN)
Cardiac arrest, AV/heart block

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prazosin

α1 antagonist
Not as much reflex tachycardia as phentomaine
prevents prostate contraction

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yohimbine

α2 antagonist

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phenylephrine

α1 agonist

-nasal decongest, dilate eye

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clonidine

α2 agonist

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dobutamine

β1 agonist

Acute heart failure, cardiogenic shock

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salbutamol

β2 agonist

asthma

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phentolamine

α antagonist
pheochromocytoma
reflex tachycardia (α2 does negative feedback, so blocking it allows more NA release, unblocked β(heart stimulating))

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propranolol + how it works

β antagonist

Reduce sympathetic outflow
↓ renin release
Block presynaptic β receptors (reduce NA release)

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metoprolol

β1 antagonist | lower blood pressure

tyramine

displace stored catecholamines from vesicles metabolized by MAO in liver indirectly acting sympathomimetic

methamphetamine

speed, not amphetamine

methylphenidate

amphetamine release DA/NA in absence of nerve activity displace stored catecholamines from vesicles indirectly acting sympathomimetic

timolol

β blocker lower IOP Reduces secretion of aqueous humor from ciliary bodies

physostigmine

Anticholinesterase lower IOP Ciliary muscle contraction, ↑ the outflow of aqueous humor

apraclonidine

similar to adrenaline effect Vasoconstrict, ↓ flow to ciliary body, ↓ secretion of aqueous humor lower IOP

anandamide

Cannabinoid endogenous ligand, CB1 and CB2 receptors | Lowers IOP by relaxing trabecular network

cromolyn

Prevent mast cell degranulation + release of inflammatory mediators

nedocromil

Prevent mast cell degranulation + release of inflammatory mediators

diphenhydramine

Benadryl, classic H1 antihistamine + sedative

dimenhydrinate

Gravol - H1 antihistamine for motion sickness

loratidine

Claritin - H1 antihistamine for seasonal rhinitis

cimetidine

H2 antagonist for stomach acid

ranitidine

H2 antagonist for stomach acid

theophylline

Antagonize adenosine, helps stop bronchoconstriction

cocaine

Inhibits DA&NA reuptake (uptake 1) Local anesthetic and hemostatic (limits bleeding & systemic absorption due to vasoconstriction) indirectly acting sympathomimetic

TCAs

Inhibit catecholamine reuptake | indirectly acting sympathomimetic

motelukast

Antagonist to IL-4 - asthma

biologics

IL-5 antibodies - asthma

what is an example of a β1 antagonist

Metoprolol

what are 2 choline esters that arent hydrolyzed by acetylcholineterase

carbachol and bethanechol

example of α1 agonist

phenylephrine

example of α2 agonist

clonidine

what is an example of a β1 agonist

dobutamine

what is an example of a β2 agonist

salbutamol

what is an example of a β agonist

isoproterenol

example of α antagonist

phentolamine

example of α1 antagonist

prazosin

example of α2 antagonist

yohimbine

what is an example of a β antagonist

propranolol

what is an example of a β1 antagonist

metoprolol

what are 2 muscarinic agonists

oxotremorine | pilocarpine

4 anticholinesterases | + 1 for glaucoma

edrophonium neostigmine malathion soman physostigmine

3 nicotinic antagonists

Succinylcholine D-tubocurarine α-bungarotoxin

3 muscarinic antagonists

atropine scopolamine ipratropium

3 directly acting sympathomimetic drugs

adrenaline noradrenaline isoproterenol

3 indirectly acting sympathomimetic drugs

amphetamine tyramine cocaine TCAs

what inhibits ACh release from vesicles

botulinim toxin

what β blocker for glaucoma

timolol

anticholinesterase for glaucoma

physostigmine

similar to adrenaline for glaucoma

apraclonidine

cannabinoid ligand, good fo glaucoma

anandamide

prevents mast cell degranulation (2)

cromolyn | nedocril

benadryl

Diphenhydramine

gravol

Dimenhydrinate

claritin

loratidine

H2 antagonists

cimetidine | ranitidine

antagonist to adenosine

theophylline caffeine

IL-4 antagonist

motelukast

IL-5 antibodies

biologics

drug names-1 Flashcards

(75 cards)