E2 Genus Staph & Strep Flashcards Preview

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Flashcards in E2 Genus Staph & Strep Deck (35)
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1

What do Staphylococcus look like?

Buch of grapes

2

How is Staph differentiated from Strep?

Catalase +
(otherwise they look similar)

3

What is are some clinical hallmarks of Staph infection?

Pimple or boil = abscess
Mastitis in cows

4

What special syndrome can be cause by a Staph infection?

Toxic Shock

5

What are the coagulase & B-hemolysis of S. aureus?

Coag = +
B-Hemo = +

6

Are Staph commensals and only opportunistic pathogens?

Yes

7

What is special about some colonies of Staph?

Live in biofilms

8

What factors of Staph are most important for pathogenesis?

1. Protein A = avoids phagocytosis
2. Survives intracellularly in phagocytes

9

What are some soluble virulence factors?

Leukocidin
Catalase
Coagulase
DNase

10

What is Toxic Shock Syndrome?

Superantigen activation

11

Is antibiotic resistance a major problem in Staph?

Yes!
Methicillin Resistance
Use Vancomycin!

12

What is positive about food animals harboring drug resistant Staph?

Isolates are host-adapted!

13

What is Staphylococcus hyicus?

Greasy Pig Disease
Esp. piglets

14

What is Staphylococcus pseudintermedius?

Canine skin infection
Normally commensal

15

Are Strep bacteria commensals?

Yes!

16

What is different about the arrangement of Strep cocci?

Chains!

17

What are the three types of Strep hemolysis?

1. Beta = complete
2. Alpha = partial
3. Gamma = NONE

18

Are Lancefield groupings related to virulence?

No. Just random groups!

19

What are M-proteins?

Strep proteins
Related to hemolysis

20

What is Strep's most important virulence factor?

Capsule!

21

Is M-protein a virulence factor?

No!

22

Where do Strep like to live?

Mucus membranes and intestines

23

How does Strep spread through tissues?

Digest fibrin clots

24

What does M-protein do?

Help Strep avoid phagocytosis

25

Do Strep survive inside phagocytes like Staph?

No cannot survive inside

26

What is Strep agalactiae?

Mastitis in cows
Detect B-hemolysis in bulk tanks
40% of mastitis infections

27

What is Strep zooepidemicus?

Common cause of wound infections in horses
Can cause arthritis

28

What is Strep equi?

Strangles in horses
Streptolysins kill phagocytes

29

How is Strep equi diagnosed?

PCR detects M-protein
Need 3 neg tests in a row to be declared nagative

30

Is there a vaccine for Strep Equi?

Yes, but NOT a DIVA vaccine