E2 Family Spirochetaceae Flashcards Preview

Bacteriology > E2 Family Spirochetaceae > Flashcards

Flashcards in E2 Family Spirochetaceae Deck (42)
Loading flashcards...
1

What is the gram reaction of the family Spirochaetaceae?

Gram negative

2

What is special about the morphology of bacteria in the family Spirochaetaceae?

Long long helical rods

3

Where are bacteria in the family Spirochaetaceae commonly found?

1. Environment
= water, soil, vegetation
2. Commensals of many animals

4

What is important about the metabolism of bacteria in the family Spirochaetaceae?

Anaerobic
(but aerotolerant)

5

What is the best diagnostic test for bacteria in the family Spirochaetaceae?

Serology

6

How are bacteria in the family Spirochaetaceae identified?

1. Number of turns
2. Overall length
3. Type of motility

7

What animals is infected with Brachyspira hyodysenteriae? What is the name of the disease?

Pigs
Swine Dysentery "bloody scours"

8

What is the route of transmission of Brachyspira hyodysenteriae?

Fecal-oral

9

What tissue does Brachyspira hyodysenteriae colonize?

Colon

10

Why is Brachyspira hyodysenteriae infection so pathogenic?

Bacteria release endotoxin & hemolysin

11

What age is most affected by infection with Brachyspira hyodysenteriae?

Older weaned piglets

12

What is the best diagnostic test for Brachyspira hyodysenteriae infection?

PCR

13

What is unique about the pathogenesis of Brachyspira hyodysenteriae infection?

It requires other bacteria to cause disease!
(no disease in pigs sole infected with B hyodysenteriae)

14

What other animal may spread Brachyspira hyodysenteriae infection?

Birds may spread the disease between farms

15

What disease is caused by Brachyspira pilosicoli?

Porcine colonic spirochetosis

16

How severe is the disease in pigs caused by Brachyspira pilosicoli?

Only some diarrhea

17

What is unique about the culturing of genus Leptospira?

Requires B vitamins

18

What is special about the growth of Leptospira interrogans?

It has two phases

19

What are the two growth phases of Leptospira interrogans?

1. Leptospiremia (1 week)
2. Leptospuria (months)

20

Where is the primary site of replication for Leptospira interrogans?

Liver

21

Can infection with Leptospira interrogans affect pregnancy?

Yes

22

How does Leptospira interrogans enter the body?

Through cuts in the skin

23

What animals are affected by Leptospira interrogans infection?

All domestic species

24

How does Leptospira interrogans evade host immunity?

Hides in immune privileged sites
(kidneys, eye, brain)

25

Is there a vaccine for Leptospira interrogans?

Yes
(but short term protection)

26

Are humans at risk for Leptospira interrogans infection?

Yes
(but it is rare)

27

What is important about the Spirochaetaceae genus Borrelia?

Tick transmission

28

What animals are infected by Borrelia anserina? What disease does it cause?

Chickens, turkeys, geese, etc
Fowl Spirochetosis

29

What is the most important clinical sign of Borrelia anserina infection?

Swollen spleen
(green-yellow diarrhea)

30

What is the best way to control Borrelia anserina infections?

Tick control