E2 Genus Mycobacteria Flashcards Preview

Bacteriology > E2 Genus Mycobacteria > Flashcards

Flashcards in E2 Genus Mycobacteria Deck (25)
Loading flashcards...
1

What is special about the staining of Mycobacteria?

Acid-fast
= unique outer membrane
= NOT capsule

2

What is the Gram stain of Mycobacteria?

Gram (+)
Rods!

3

What is unique about the growth of Mycobacteria?

VERY slow

4

What special component do Mycobacteria have in their cell wall?

Mycolic acid

5

How do Mycobacteria avoid death by phagocytosis

Blocks acidification of phagolysosome

6

What kind of lesions are caused by Mycobacteria?

Granulomatous tubercles

7

What is Mycobacteria bovis?

Bovine TB
ZOONOTIC
Affects many species

8

How long before clinical signs appear of infection with Mycobacteria bovis?

1-5 years!

9

What is the definitive diagnosis for Mycobacteria bovis?

Culture
but PCR is useful
after TB skin test

10

What is a comparative DTH test?

Compare bovine reaction to both M. avium and M. bovis
If blebs are the same size = no infection

11

What species is most likely to infect cattle with Mycobacteria bovis?

Deer

12

Does pasteurization kill Mycobacteria bovis?

Unclear

13

Can cattle infected with Mycobacteria bovis be treated?

NO!
It's illegal!
Only depopulation

14

What is Mycobacterium avium ssp. paratuberculosis (MAP)?

Johne's disease

15

What is the prevalence of Johne's or MAP in cattle?

8% in beef
22% in dairy herds

16

Can Johne's/MAP affect other species?

Yes
Goats = no hyperproliferation
Humans = Crohn's disease??

17

How long does it take for clinical signs to appear in animals with Johne's/MAP?

1-3 years

18

What are the clinical signs of Johne's/MAP?

1. Emaciation but normal appetite
2. Bottle jaw
3. Lymph nodes
4. Rough dry coat

19

What part of an infected animal is most infectious?

Feces!
Also milk, urine, semen

20

Is there a vaccine for Johne's/MAP?

No!

21

What is the definitive test for Johne's/MAP?

Fecal culture
BUT tests are NOT accurate until Stage III disease!

22

Is Johne's/MAP reportable?

Yes!

23

Is there a vaccine for Johne's/MAP?

No official vaccine
Can vaccinate with heat killed organisms

24

What are good biosecurity practices for Johne's/MAP?

Removes calves shortly after birth
Use housing that can be disinfected
Purchase new animals that are > 3 yrs

25

What is Mycobacterium lepraemurium?

Leprosy-like disease in cats