Endocrine and Aging Flashcards Preview

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Flashcards in Endocrine and Aging Deck (16)
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1
Q

Menopause

A

E2 declines –> happens when run out of eggs

2
Q

Andropause

A

T declines

3
Q

Adrenopause

A

DHEA declines but no change in cortisol or ACTH

4
Q

Somatopause

A

GH/IGF1 declines

5
Q

Estrogen/progesterone combined tx after menopause increases/decreases: breast cancer, stroke, CAD risks

A

increases relative risk of all of them

6
Q

ERT increases/decreases: CHD, CA, stokre, VTE, hip fx

A

decreases risk –> but globally no risk or benefit

7
Q

T/F ERT can prevent dementia

A

F –> no difference in global cognitive function

8
Q

T/F low dose ERT during peri/menopause is relatively safe

A

T –> but not after long period without estrogen (e.g. 70 year old woman)

9
Q

bioidentical hormones

A

compounds that have the same structure as those in human body –> promoted as safer and more effective alternatives to traditional hormone therapies

10
Q

Increase or decrease with age in men? LH amplitude, frequency, basal

A

decrease amplitude, increased frequency, increased basal

11
Q

Is there a benefit to DHEA replacement?

A

no real evidence for benefits or risks

12
Q

Nocturnal minimal cortisol in older people is higher/lower

A

higher –> overall higher exposure to cortisol –> muscle loss, adiposity, less REM

13
Q

T/f older people are more likely to have an abnormal 2 hour glucose on GTT

A

T

14
Q

T/F evidence demonstrates subclinical hypothyroidism increases risk of CVD

A

F

15
Q

There are age associated increase/decrease in nocturnal cortisol and glucose intolerance

A

increase

16
Q

T/F harder to recognize hyper or hypothyroidism in older people

A

T –> non classical presentation