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Flashcards in Endocrine and Aging Deck (16):
1

Menopause

E2 declines --> happens when run out of eggs

2

Andropause

T declines

3

Adrenopause

DHEA declines but no change in cortisol or ACTH

4

Somatopause

GH/IGF1 declines

5

Estrogen/progesterone combined tx after menopause increases/decreases: breast cancer, stroke, CAD risks

increases relative risk of all of them

6

ERT increases/decreases: CHD, CA, stokre, VTE, hip fx

decreases risk --> but globally no risk or benefit

7

T/F ERT can prevent dementia

F --> no difference in global cognitive function

8

T/F low dose ERT during peri/menopause is relatively safe

T --> but not after long period without estrogen (e.g. 70 year old woman)

9

bioidentical hormones

compounds that have the same structure as those in human body --> promoted as safer and more effective alternatives to traditional hormone therapies

10

Increase or decrease with age in men? LH amplitude, frequency, basal

decrease amplitude, increased frequency, increased basal

11

Is there a benefit to DHEA replacement?

no real evidence for benefits or risks

12

Nocturnal minimal cortisol in older people is higher/lower

higher --> overall higher exposure to cortisol --> muscle loss, adiposity, less REM

13

T/f older people are more likely to have an abnormal 2 hour glucose on GTT

T

14

T/F evidence demonstrates subclinical hypothyroidism increases risk of CVD

F

15

There are age associated increase/decrease in nocturnal cortisol and glucose intolerance

increase

16

T/F harder to recognize hyper or hypothyroidism in older people

T --> non classical presentation