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Flashcards in Endocrinology Basics Deck (16)
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1

what are the different endocrine glands

thyroid, pituitary, adrenal, parathyroid, pancreas, ovaries/testes

2

what are the main subtypes of hormones

protein and polypeptide hormones, steroid hormones(lipid derived), amino acid derived

3

what are some examples of protein and polypeptide hormones

oxytocin, insulin, growth hormone, FSH

4

give some examples of amino acid derived hormones

tyrosine, adrenaline, tryptophan

5

give some examples of steroid hormones

testosterone, cortisol, oestradiol, aldosterone

6

what are the 4 main groups of hormone receptor

G protein coupled receptors(GCPR), Receptor tyrosine kinase(RTK) families, Receptors associated with tyrosine activity, Steroid receptors

7

what type of receptor is insulin receptor

intrinsic tyrosine kinase receptor

8

what do steroid receptors result in

changes in gene transcription

9

what is the role of the hypothalamic pituitary gland

key regulator of majority of hormones

10

what does the accurate measuring of hormone levels depend on

interfering agents, stability of hormone(eg half life), absolute conc., pattern of secretion, presence of carrier proteins

11

what is the major determinant of hormone conc.

rate of secretion

12

what types of hormones are typically measured and regulated

thyroid hormones, steroid hormones, growth hormone, reproductive/sex hormones, prolactin, calcium/parathyroid hormone

13

what is tested to evaluate thyroid hormone

TSH assay, if raised = hypothyroidism, if suppressed hyperthyroidism
(not reliable if pituitary gland not working)

14

what type of control system is found throughout endocrinology

negative feedback loops

15

what are some of the different blood tests that can be used to assess pituitary gland function

TSH, prolactin, 9am cortisol, IGF1, testosterone/E2, U&E, plasma

16

where is prolactin secreted from

lactotroph cells in anterior pituitary