Hypothalamic Pituitary Axis Physiology Flashcards Preview

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Flashcards in Hypothalamic Pituitary Axis Physiology Deck (16)
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1

what lobe of the pituitary gland is directly linked to the hypothalamus

posterior

2

what hormones are secreted by the posterior lobe of the pituitary and where are they produced

ADH and oxytocin, they are produced in hypothalamus and stored in pituitary until needed
(ADH also called Vasopressin)

3

what is the role of ADH

controls thirst and urine output

4

what are the roles of oxytocin

males = control smooth muscle in ductus deferens and prostate gland
females = control uterine smooth muscle and mammary glands

5

how is the anterior lobe of the pituitary linked to the hypothalamus

by blood vessels, portal system between the two

6

what hormones are secreted from the anterior lobe of the pituitary

ACTH, TSH, GH, PRL, FSH, LH, MSH

7

what hormone is released from the hypothalamus to stimulate TSH release from the pituitary

Thyrotropin-releasing hormone(TRH)

8

give examples of hormones that have a negative feedback loop with the pituitary gland

thyroxine, testosterone/oestrogen, cortisol

9

describe the steroid hypothalamic pituitary axis

Hypothalamus secretes CRH, stimulates pituitary to secrete ACTH, which promotes cortisol release at adrenal gland, cortisol acts on tissues

10

describe the thyroid hypothalamic pituitary axis

Hypothalamus secretes TRH, stimulates pituitary to secrete TSH, which promotes T4 release at thyroid, T4 acts on tissues

11

describe the sex hormone hypothalamic pituitary axis

Hypothalamus secretes GnRH, stimulates pituitary to secrete LH/FSH, which promote release of testosterone or oestrogen, test/e2 act on tissues

12

describe the growth hormone hypothalamic pituitary axis

Hypothalamus secretes GHRH, stimulates pituitary to release GH, GH acts on tissues

13

describe the prolactin hypothalamic pituitary axis

Hypothalamus secretes DA(dopamine), suppresses prolactin secretion from pituitary, prolactin acts on tissues

14

what is the only hypothalamic hormone axis that has suppressant effect rather than stimulating on pituitary hormone release

dopamine in prolactin axis

15

what is the name give to the paired hormones to the pituitary hormones and give an example

peripheral hormones, eg TSH is pituitary and T4(thyroxine) is peripheral hormone

16

what is meant by dynamic testing of hormones, as opposed to baseline testing

dynamic is to do a test that tries to suppress or stimulate a hormone, rather than just measuring baseline levels