Eryspielothrix - Exam 2 Flashcards Preview

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Flashcards in Eryspielothrix - Exam 2 Deck (20):
1

Which species does Erysipelothrix rhusiopathiae most commonly infect?

Swine

Pigs less than 3 months and over 3 years of age are least susceptible 

The pigs that are most susceptible have not developed their full immune response and are commonly when the pigs are pushed for production and animals are stressed

(also infect turkey and sheep)

2

True/False. Erysipelothrix rhusiopathiae are very persistent in the environment.

TRUE!

Can survive for 6 months in swine feces

Resistant to drying and high salt concentrations

Can survive in a wide range of temperatures

3

How do turkey and sheep become infected with Eryispelothrix rhusiopathiae?

Usually with wound infections

Males are more frequently infected (fight wounds)

4

What is the most important virulence factor of E. rhusiopathiae and what is its function?

Neuraminidase

Cleaves sialic acid from epithelial cells and allow the bacteria to bond and leads to thrombus formation

Its production varies directly with its virulence

5

How is E. rhusiopathiae transmitted to swine?

Mainly by ingestion of contaminated material

6

Which form of of Erysipelothrix is acute and associated with high mortality in swine?

The septic form

Fever, anorexia, depression, vomiting, stiff gait, reluctance to walk, palpable urticarial lesions are felts before visible

7

What kind of kind of lesions are associated with the most common form for Erysipelothrix in swine?

Diamond skin diseases

Acute and less severe

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8

Which form of Erysipelothrix has a significant impact on swine industry?

Chronic forms

Vegetative endocarditis (cardiac insufficiency or sudden death)

Arthritis 

Abortion (infrequent)

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9

True/False. Erysipelothrix will be included in the differential diagnosis if a turkey presents with a swollen snood.

True

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10

Which bird species does Erysipelothrix typically infect and what does it cause?

Turkeys! 

Usually causes septiciemia 

Chronic manifestations include vegetative endocarditis and arthritis

11

True/False. Humans can become infected by Erysipeolthrix through zoonosis.

True!

Usually from handling infected fish or meat! (self-limiting infection on the skin-hand)

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12

What pathogenesis will you see with Erysipelothrix in dolphins?

Septicemia and urticaria

13

What pathogenesis will you see with Erysipelothrix in dogs?

Endocarditis and arthritis 

14

What type of pathogenesis will you see in sheep with Erysipelothrix? How do they become infected?

Polyarthritis

Entry through umbilicus or wound

Affected animals show stiff gait and swollen joints

15

What is the target for the cell-mediated and humoral response?

Neruaminidase!!

Antibodies will bind to the neuraminidase which will not let it cleave the sialic acid and bacteria cannot bind 

"killed by complement and other shit"

16

What type of organism would you expect to see when you look at a Erysipelothrix gram stain?

Gram-positive slender rods

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17

What kind of hemolysis would you expect to see when you culture Erysipelothrix?

Gamma hemolysis

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18

Erysipelothrix produces _________ and is coagulase _______.

Erysipelothrix produces hydrogen sulfide and is coagulase POSITIVE.

19

True/False. The acute form of Erysipelothrix is easier to treat than the chronic form.

True

20

True/False. The best way to stop the spread of Erysipelothrix is to prevent it.

True