Klebsiella - Exam 2 Flashcards Preview

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Flashcards in Klebsiella - Exam 2 Deck (17):
1

Klebsiella is a gram _____ bacteria.

Negative

2

Which virulence factor of Klebiella is responsible for fever, neutropenia, petechia and shock?

Endotoxin - lipid A

3

Which virulence factor is essential to Kelbsiella and binds to epithelial cells in urinary and respiratory tracts?

The capsule

4

What is the most common bacterial isolate from non-human primates with pneumonia?

K. pneumoniae

5

How is Klebsiella transmitted?

Many species it is transferred by wound infections, especially when skin or mucosae are breached by dz, trauma, burns, ect

6

What economincally significant disease does Klebsiella cause in ruminants?

Bovine mastitis 

Case fatality as high at 80%

7

What diseases does Klebsiella cause in horses?

Reproductive tract disease (vaginitis, inferitilty, metritis and abortion)

Navel ill (common in animals that failed passive transfer)

8

What are the diseases that Klebsiella commonly causes in dogs?

Pyometra, systitis, prostatitis, meningoencephalitis, enteritis, mastitis and hepatic abcessation

9

What diseases does Klebsiella cause in pet birds?

Respiratory infections, septicemia and diarrhea

10

What diseases does Klebsiella cause in reptiles?

Pneumonia and hypopyon

(hypopyon - inflammatory cells in the anterior chamber of eye)

11

What does Klebsiella cause in guinea pigs?

Septicemia

12

What makes the bacteria more invasive and more resistant to phagocytosis?

Capsular serotypes K1 and K2 that carry genes MagA and rmpA

(MagA - mucoviscosity-associated gene/K1 specific capsular polymerase gene)

(rmpA - regulator of mucoid phenotype)

13

What causes septic shock with Klebsiella?

DIC 

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14

What species of monkeys in St. Kitts is Klebsiella prevalent in?

Vervet monkeys

Abscesses everywhere found in a Vervet onkey with pus present in the abdominal cavity

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15

What is indicative of capsule ona bacteriological culture of Klebsiella?

Large mucoid viscous colonies on blood agar

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16

How would you prevent and control Klebsiella for cows?

Avoid sawdust or wood shaving bedding

17

How do you prevent nosocomial infectinos of Klebsiella?

Improve hand washing, sterilization procedures, closed-system urinary drainage, reduce prophylactic use of antibiotics