Exam 2 Study Guide Flashcards

1
Q

Where are cell bodies of UMN?

A
  • cerebral cortex

- brainstem

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2
Q

Where do UMN axons travel?

A

in pyramidal tracts

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3
Q

UMN axons synapse with

A
  • interneurons
  • LMN

in brainstem or SC

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4
Q

LMN cell bodies are located here (big picture)

A
  • spinal cord

- brainstem

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5
Q

alpha LMNs innervate

A

extrafusal fibers

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6
Q

gamma LMNs innervate

A

intrafusal fibers

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7
Q

coactivation of alpha and gamma LMN

A

maintain stretch on intrafusal fibers while extrafusal fibers contract

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8
Q

mechanisms of sensory contribution to motor systems

A
  • feedback

- feedforward

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9
Q

feedforward

A

anticipatory use of sensory info to prepare for movement

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10
Q

feedback

A

use of sensory info during or after movement to make corrections to ongoing movement or future movements

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11
Q

When does neural transmission to a muscle fiber stop?

A

when ACH is removed from the synaptic cleft

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12
Q

How does ACH removal occur?

A
  • diffusion away from the synapse

- broken down by acetylcholinesterase to acetic acid and choline

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13
Q

sequence of events that converts APs in a muscle fiber to a contraction

A

excitation contraction coupling

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14
Q

2 terminal cisternae + 1 t-tubule

A

triad

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15
Q

motor pathway overall

A
  • decision from frontal cortex
  • motor planning areas
  • control circuits
  • UMN conducts signals to LMN and interneurons
  • LMN » skeletal muscles
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16
Q

amount of tension in a muscle at rest

OR

amount of resistance to passive stretch exerted by a resting muscle

17
Q

How is tone acquired?

A
  • weak actin-myosin bonds
  • titin
  • active contraction
18
Q

How do muscles adapt to changes in length?

A

They are plastic/adaptable. When contracted or extended for a period of time, they either lose or gain sarcomeres

19
Q

What happens to someone who has had their arm in a cast or sling for 6 weeks?

A
  • contracture

- greater resistance to stretch

20
Q

What happens to someone who suffers from spasticity (as in CP)?

A
  • muscle more difficult to stretch

- spastic co-contraction makes it hard to walk

21
Q

How does the spinal region contribute to movement?

A
  • reflexes
  • stepping pattern generators
  • inhibitory interneuron circuits
22
Q

Activation of ceruleospinal and raphespinal tracts produces

A

produce a generalized increase in activity of

  • spinal interneurons
  • motor neurons
23
Q

contribution of ceruleospinal and raphespinal tracts overall

A

may contribute to poorer motor performance when anxiety is high

24
Q

ceruleopinal and raphespinal tracts (example)

A

Climbers on a high wall move more slowly, make more exploratory movements, and use each hold longer than those on a lower climbing wall

25
What reduces the rate of postural adjustments?
fear
26
paresis
partial loss of voluntary movements
27
paralysis
total loss of voluntary movements
28
muscle atrophy
loss of muscle bulk
29
2 types of atrophy
- disuse | - neurogenic
30
disuse atrophy
lack of muscle use
31
neurogenic atrophy
damage to nervous system
32
spasm
sudden, involuntary contraction of muscle fibers
33
cramp
severe, painful muscle spasm
34
fasciculations
- quick twitches of muscle fibers of single motor units | - visible on surface of skin
35
hypotonia caused by
- LMN lesions | - acute UMN lesions
36
hypertonia caused by
chronic UMN lesions
37
hyperreflexia
UMN problem - loss of inhibitory corticospinal input - excessive interneuron and LMN activity
38
hyporeflexia
LMN problem