Exam 3-15 Flashcards Preview

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Flashcards in Exam 3-15 Deck (15)
1

parvalbumin = ______ buffer

cytoplasmic

2

calsequestrin = _______ buffer

ER/SR

3

Calmodulin

binds to and confers Ca2+ regulation to large number of other proteins (L hand motif found in parvalbumin, calpain and troponin)

4

cytopalnine

cancer drug that kills cancer and stem cells

5

abiraterone acetate

CMP17 inhibitor that decreases testosterone levels

6

enzalutamide

new generation AR antagonist

7

GAGs

covalent linkage to proteins --> proteoglycans
-amno sugar + uronic acid
-high neg charge

8

fibrolyproteins

elastin

9

multiclonar adaptor proteins

fibronectin and laminin

10

PGs

high molecular weight, core proteins = serine, tetrasaccharides, filtering of glomerulus and reservoir or GF and proteases

11

Aggrecan

assembly of PGs and GAGs

12

collagens I and IV

I connective tissues, IV = basal lamina

13

fibronectin =

dimeric glycoprotein, S-s, Arg-Gly-Asp, forms fibrils

14

laminin

3 subunits (ABG) S-S, basal lamina, self assembly

15

MMP function

turn over ECM