Flashcards in Exam 3-16 Deck (8)
Loading flashcards...
1
CAMs
when bound to a ligand have a conformational change, form TM link
2
cadhedrin
single pass TM glycoprotein that operates as a homodimer, Ca2+ dependent
3
IgSF
single pass TM glycoprotein, homophobic binding, no dimers, no Ca2+
4
integrins
"classic" AMs, heterophilic, A/B heterodimer
5
CAMS linked to cytoskeleton and also regulate
adhesion, control actin polymerization, mediate cell signaling
6
in development, CAMs change as ___________
cells differentiate
7
ECM and disease
-collagen= osteogenesis and skeletal dysplasias
-lamin= nephrotic syndrome and neuromuscular junction/muscular problems in children
-MMP - LOF mutations 2 or 13 = osteolysis/arthritis/bone diseases
8
