Exam 3-5 Flashcards Preview

M2M Unit III > Exam 3-5 > Flashcards

Flashcards in Exam 3-5 Deck (15)
1

n-sec1

refolds syntaxin into active formation

2

NSF and alpha-SNAP

disassemble protein
NSF uses ATP hydrolysis

3

VAMP location

transport vesicle

4

SNAP location

target membrane

5

syntaxin location

target membrane

6

HIF is a ____ that is _____ dependent.

TF
oxygen

7

HIF-alpha is ______ by ___ and ___

hydroxylated by proline and aspraganine

8

VHL _____ normal HIF-alpha

ubiq

9

use _______ to target downstream GFs of HIF and ______ to target mTOR

S-------nib
______lumin

10

VHL is a

tumor suppressor

11

sign of VHL

hemangioloastomas

12

Type 1, 2A and 2B ____regulate HIF

up

13

Type 2C ____regulates HIF

down

14

most VHL are

clear cell sporadid

15

VHL chromosome and what else is on it

3p
also on this are BAP 1 and PRBM1