Exam 4: Digestive System Flashcards

(45 cards)

1
Q

functions of the digestive system

5 primary, 2 associated

A

primary:
-ingestion, movement of food, digestion (mechanical and chemical), absorption, and excretion
associated:
-immune defense, endocrine secretions

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2
Q

composition of the digestive system

A
alimentary canal (digestive tract) - tube within a tube
accessory organs:
tongue, teeth, salivary glands, liver, gallbladder, pancreas

lumen of alimentary canal considered functionally external to the body

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3
Q

histology layers (4)

A

mucosal
submucosa
muscularis externa
serosa/adventitia

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4
Q

mucosal layer

A

-mainly epithelium - changes
depending on where you are
-basement membrane supporting it: lamina propria
-muscularis mucosa: muscle layer around, shape and secretions in layer

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5
Q

epithelium in stomach, esophagus, intestine, rectum

A

stomach: columnar cells
esophagus: non keratinized stratified squamous
intestine: villi in columnar
rectum: nonkeratinized stratified squamous

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6
Q

submucosa layer

A

dense, irregular connective tissue that supports the glands and blood vessels

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7
Q

muscularis externa layer

A

circular muscle and longitudinal muscle
work together to give peristalsis waves
-circular would constrict and longiudinal would push it along

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8
Q

serosa/adventitia layers

A

serosa: stomach and intestines, serous membranes that lubricate and protect, secretes fluid to avoid rubbing

adventitia: pharynx, esophagus, rectum
protective CT layer - no serous secretions, in places where no rubbing should occur

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9
Q

enteric plexus - autonomic nervous system

A

parasympathetic: inc muscle activity, tone, gland secretions
sympathetic: dec all activity - directs blood flow to skeletal muscle
stress can cause GI distress

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10
Q

enteric plexus is formed by 2 separate plexuses

A

submucosa and myenteric

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11
Q

submucosa plexus

A

contains stretch and chemical receptors
controls shape of mucosa ad degree of secretion

-closer to the lumen, sensitive to what moves through lumen

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12
Q

myenteric plexus

A

located between circular and longitudinal muscle layers

controls paristalsis
-faster if higher motility, slower if you want to process food slowly

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13
Q

oral cavity components and functions

A

components: tongue, teeth, gingiva, tonsils
receives secretions from salivary glands

site of mastication (chewing)
beginning of chemical digestion

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14
Q

dentition - adult

A

adult: 2,1,2,3/2,1,2,3 x2
2 incisors, 1 canine, 2 premolars, 3 molars
long roots

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15
Q

dentition-deciduous/baby teeth

A

2,1,2/2,1,2 x 2
short roots
only 3 types of teeth - no premolars

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16
Q

tooth anatomy - regions

A

root: embedded in bone
- well into alveolar process of mandible or maxilla
neck: protected by gum tissue
- sensitive to decay since not well protected by crown
crown: external surface
- strong and protective, enamel

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17
Q

root canal

A

contains pulp (blood vessels and nerve)

  • of decay in this you can get abscess bacteria in bloodstream
  • if infected may have to get a root canal - they remove the pulp
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18
Q

dentin

A
  • secretory cells in channels
  • cells secrete cementin to attach to socket
  • produce periodontal ligaments
  • matrix similar to bone by higher % of hydroxyapatite
  • if lose a tooth you lose the stimulation to alveolar process area and can lose bone mass
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19
Q

enamel

A

hardest substance in body (97% hydroxyapatite)
cells degenerate after production
-important to keep enamel healthy, if it wears away you get access to dentin and can get cavities

20
Q

why is saliva produced? (3)

A

chemical digestion
lubrication of food
defense of oral cavity

21
Q

saliva composition

A
water
electrolytes and buffer
mucins- lubrication of food 
antibodies (IgA)
enzymes
22
Q

types of salivary enzymes (2)

A

salivary amylases: begins carbohydrate digestion

lingual lipase: begins lipid digestion

both inactived in stomach acid environment

23
Q

functions of tongue and ulva

A

tongue: positions food, aids in forming bolus, contains taste buds
ulva: prevents food from entering nasopharynx

24
Q

3 phases of deglutition

A

both voluntary and involuntary reflex

buccal phase, pharyngeal phase, esophageal phase

25
buccal phase of deglutition
1st phase | tongue compresses bolus against hard palate and begins to move bolus back (voluntary!!)
26
pharyngeal phase of deglutition
2nd phase tongue depresses and moves bolus into oropharynx contacting pharyngeal arches (now INVOLUNTARY action begins!!) larynx lifts as epiglottis closes glottis upper esophageal sphincter opens
27
esophageal phase of deglutition
3rd phase bolus enters esophagus and peristalsis takes over upper esophageal sphincter closes larynx returns to position with glottis open breathing can resume
28
esophagus
moves bolus though peristalsis | nonkeratinized startified squamous of mucosa does not have goblet cells
29
2 extra layers of lubrication and protection for esophagus
submucosal glands: secrete mucus in upper part of esophagus, lubricates esophageal lining cardiac glands: in lamina propria of esophogastric junction - protects lower esophagus from reguritated acidic gastric secretions - pyrosis (heart burn, acid reflux) occurs when secretions overwhelmed
30
regions of the stomach
4 or 5 -cardac -fundus (collects gas) -body: most digestion in stomach here, rugae -pyloric region: where chyme getting ready to leave stomach can be divided in 2: antrum: till mixing wih gastric secretion and pyloric canal: getting ready to go into SI
31
the environment of the adult stomach is maintained at a pH between
1.5 and 2
32
digestive action of the stomach
- bolus enters, subjected to peristaltic waves that mix the food with mucous secretions in fundus forming chyme. salivary digestion continues - stretch receptors stimulate G-cells to release gastrin - gastrin activates chief and parietal cell secretions - chief cells release pepsinogen - HCl from parietal cells activates pepsinogen to form pepsin pH 2 - Parietal cells release intrinsic factor to bind V B12 - inc gastrin results in inc stomach motility - chyme mixes with gastric secretions
33
what do stretch receptors stimulate
G cells to release gastrin
34
what does gastrin activate
chief and parietal cells
35
chief cells release
pepsinogen
36
what does HCl from parietal cells activate
pepsinogen to pepsin pH2
37
what to parietal cells release
intrinsic factor to vitamin B12
38
what enters the bloodstream during a large meal due to inc stimulation of parietal cells
alkaline tide | chloride shift, bicarb going out , makes you tired
39
stomach action in an infant
can only get a pH of 5 modified chief cell secretions: - renin released- in presence of Ca, acts on casein protein in milk to form curds alpha and beta stay soluble due to kappa renin breaks kappa - not soluble, curds - gastric lipase: digests milk fat - both secretions optimal at pH 5
40
3 phases in stomach response
cephalic, gastric, intestinal
41
cephalic phase - stomach response
gastric secretions begin in response to thinking, smelling or seeing food - have not ingested yet
42
gastric phase- stomach response
- stretch receptors directly trigger G cells and indirectly trigger parietal and chief cells - chemoreceptors monitor pH level (can be stimulated by anxiety, caffeine)
43
intestinal phase - stomach response
- regulation of stomach emptying | - stretch receptors result in CCK and GIP release
44
CCK
stimulates pancreatic and gallbladder secretions
45
GIP
stimulates pancreas and slows motility of stomach in response to high fat meals