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Flashcards in Exam Deck (17):
1

Diagnostic tests for viral meningitis? (3)

Viral culture of throat swab, stool
Viral PCR on CSF

2

Distinguishing features of viral encephalitis? (2)

Focal neurological deficit
Decreased GCS

3

Important features of the history to ask about in viral encephalitis? (2)

Recent travel, occupational exposure

4

Bacterial meningitis causative organisms:
a) old/immunosuppressed
b) neonates
c) young children/ older childen/adults

a) consider listeria, TB
b) group b strep, listeria, E.coli
c) pneumococcal, meningococcal

5

Initial blind antibiotic therapy in suspected bacterial meningitis

IV cefotaxime + amoxicillin if listeria suspected
Also give steroids with first dose

6

Antibiotic for confirmed meningococcal meningitis

Benzylpenicillin/ampicillin

7

When is meningitis contact prophylaxis required and what is given?

Meningococcal; ciprofloxacin

8

70% of mutations in Duchenne MD are..

Large deletions in the dystrophin gene

9

What area of the brain is atrophied prominently in Huntingtons?

The caudate nucleus

10

Genes causing autosomal dominant Alzheimers (3)

APP
presenilin 1 and 2

11

Bilateral acoustic neuromas are a sign of what inherited condition?

Neurofibromatosis 2

12

Features which distinguish tuberous sclerosis from NF?(3)

Shagreen patches
Subungual fibromas
Epilepsy

13

CT findings in subdural haemorrhage

Crescent-shaped hyperdensity (acute) or hypodense (chronic)

14

Surgical management of subdural haemorrhage

Burr hole
Craniotomy + drainage

15

Medical conditions which predispose to Berry aneurysms?

Ehlers-Danlos
adult polycystic kidney disease

16

Feature of the history/imaging which points strongly to a diagnosis of extra dural haemorrhage?

Lucid period

Imaging- lentiform hyperdensity (limited by skull sutures)

17

What is the commonest cause of encephalitis and what area of the brain does it usually affect?

Herpes simplex; temporal lobe