Eye Pharmacology Flashcards Preview

Neuro > Eye Pharmacology > Flashcards

Flashcards in Eye Pharmacology Deck (14):
1

Phenylephrine

-Alpha 1 agonist (mydriatic agent)

2

Atropine

- Muscarine antagonist (blocks parasympathetic activity)
-Mydriatic agent

3

Amphetamine

-Releases norepinephrine from post-ganglionic sympathetics
-Mydriatic agent if postganglionic nerve is present (because postganglionic nerve contains norepinephrine)

4

Cocaine

-Prevents norepinephrine uptake into the nerve
-Mydriatic agent if nerves work
*lack of pupil dilation indicates defect in sympathetic innervation (Horner Syndrome)

5

What is a potential side effect of any mydriatic agent?

It can precipitate closed angle glaucoma

6

Pilocarpine

-Muscarinic agonist (miotic agent)

7

Acetylcholine

Muscarinic agonist (miotic agent)

8

Terazosin

-Alpha 1 adrenergic antagonist (miotic agent)

9

Physostigmine

-Anticholinesterase
-Miotic agent

10

Nicotine

-Miotic agent

11

True or False, muscarinic agonists (miotic agents) enhance aqueous humor outflow.

True

12

Latanaprost

-Enhances aqueous humor outflow because it is a prostaglandin derivative and it increases uveo-scleral outflow of aqueous humor (flow through the ciliary muscle)

13

What are the treatments for glaucoma?

-Pilocarpine (muscarinic agonists)
-Latanaprost (prostaglandin derivative)
-Epinephrine
-Timolol (beta adrenergic antagonists)
-Acetazolamide (carbonic anhydrase inhibitors)

14

Botulinum toxin

Suppresses acetylcholine release from nerves. Relaxes skeletal muscle. Used to treat blephorospasm or strabismus.