Flashcards in Eye Pharmacology Deck (14):
-Alpha 1 agonist (mydriatic agent)
- Muscarine antagonist (blocks parasympathetic activity)
-Releases norepinephrine from post-ganglionic sympathetics
-Mydriatic agent if postganglionic nerve is present (because postganglionic nerve contains norepinephrine)
-Prevents norepinephrine uptake into the nerve
-Mydriatic agent if nerves work
*lack of pupil dilation indicates defect in sympathetic innervation (Horner Syndrome)
What is a potential side effect of any mydriatic agent?
It can precipitate closed angle glaucoma
-Muscarinic agonist (miotic agent)
Muscarinic agonist (miotic agent)
-Alpha 1 adrenergic antagonist (miotic agent)
True or False, muscarinic agonists (miotic agents) enhance aqueous humor outflow.
-Enhances aqueous humor outflow because it is a prostaglandin derivative and it increases uveo-scleral outflow of aqueous humor (flow through the ciliary muscle)
What are the treatments for glaucoma?
-Pilocarpine (muscarinic agonists)
-Latanaprost (prostaglandin derivative)
-Timolol (beta adrenergic antagonists)
-Acetazolamide (carbonic anhydrase inhibitors)