Fatty Acid Oxidation Flashcards Preview

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Flashcards in Fatty Acid Oxidation Deck (19):
0

Fatty acids are released from the _____ of adipose tissue by ____ into the blood

Triacylglycerol
Lipase

1

Long-chained fatty acid are ______ , they can disrupt the _____ bonding between amino acid side chain I protein

Hydrophobic
Hydrophobic

2

Long chain fatty acid are transported in the blood by binding to _____

Albumin

3

in the liver, ketone bodies are synthesized in the mitochondrial matrix from _____ generated from _______

Acetyl-coA
Fatty acid oxidation

4

Ketongenic amino acid such as ____ can be catabolized into ____ or _____ to make ketone bodies

Leucine isoleucine Lysine
Acetyl-coA
Acetoacetyl-coA

5

Ketone bodies can be oxidized as fuel in all tissues except ____ and ____

Liver
Red blood cells

6

Beta oxidation generates

Acteycoa
NADH
FADH2

7

_____ activates fatty acid to fatty acyl-coA

Fatty acyl-coA synthetase

8

Oxidation of 1 mol of palmitate yields _____ acetyl coA

8

9

Oxidation of 1 mol of palmitate yields net _____ ATP, __ ATP per NADH, ___ ATP per FADH2

106
2.5
1.5

10

In oxidation of of unsaturated fatty acid, isomerase moves double bond can covert them to ___ configuration, reductase reduce double bond utilizing ____

Trans
NADPH

11

Final product of odd chained fatty acid oxidation is _______, which is converted to _____, an snapper optic route for TCA cycle

Propionyl coA
Succinyl coA

12

_____ cannot perform beta oxidation, ___ and ____ do not use fatty acid as a fuel in a significant manner

Red blood cells
Brain adipocyte

13

w-oxidation results in a ____ that is subject to beta oxidation

Dicarboxylic acid

14

The 3 pathway if a, b, and w-oxidation decrease the level of _____ fatty acid and ____ compounds with fatty acid like structure that might be toxic at high concentration

Water-insoluble
Xenobiotic

15

Very long chained fatty acid of 24 to 26 carbons are oxidized exclusively in the ______

Peroxisome

16

Branches chained fatty acid in the diet are from _______ and is oxidized in the ____ using combination of a and b-oxidation

green vegetables
Peroxisomes

17

Ketone body oxidation occurs in the ____, one ketone body is oxidized into 2 molecules of _____ to enter into TCA cycle

Mitochondria matrix
Acetyl-coA

18

Oxidation of 1 acetoacetate generate ___ AtP, oxidation of 1 b-hydroxybutyrate generate ___ ATP

19 21.5