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Flashcards in Gluconeogenesis Deck (12):
0

______ catalyzes the conversion of glucose-6-p to glucose

Glucose 6-phosphatase

1

_____ catalyzes the conversion of Fructose-1, 6 bisP to Fructose-6-P

Fructose 1,6 bisphosphatase

2

Under fasting condition, pyruvate dehydrogenase is phosphorylated to its inactive form, therefore ____ is not converted to _____

Pyruvate
Acetyl-coA

3

Acety-coA, which is produced by oxidation of ______, activates ____

Fatty acid
Pyruvate carboxylase

4

High level of ____ inhibits pyruvate dehydrogenase and activates ____

Acetyl-coA
Pyruvate carboxylase

5

Oxaloacetate produce PEP in a reaction catalyzes by _____

PEP carboxylase

6

When glucagon level is elevated, liver pyruvate kinase is _____ and inactivated by a mechanism that involves ___

Phosphorylated
cAMP

7

Insulin activates the phosphatase that _____ glycogen synthase and ____ glycogen phosphorylase

Activates
Inhibit

8

Insulin promotes the synthesis of the_____ that are released from the liver into the blood as ____

triacylglycerols
VLDL

9

Insulin stimulates the transport of glucose into ____ and _____

Muscle
Adipose tissue

10

Under fasting condition, fatty acid and glycerol are released from triacylglycerols store of _____, fatty acid travel to the ____ where thy undergo beta oxidation

Adipose tissue
Liver

11

Pyruvate carboxylase requires ____ as cofactor

Biotin