Female 1 Flashcards Preview

Anatomic pathology > Female 1 > Flashcards

Flashcards in Female 1 Deck (255)
Loading flashcards...
1

Mesonephric-like vulvar cyst:

A. Lining.
B. Wall.
C. Contents.

A. Cuboidal or columnar

B. Smooth muscle.

C. Clear fluid.

2

Ciliated vulvar cyst:

A. Lining.
B. Wall.

A. Ciliated and secretory columnar; may be pseudostratified.

B. No smooth muscle.

3

Periurethral cyst: Lining.

Transitional epithelium.

4

Hidradenoma papilliferum:

A. Synonym.
B. Age group.

A. Papillary hidradenoma.

B. Middle age.

5

Hidradenoma papilliferum: Origins (2).

Apocrine sweat glands.

Ectopic breast tissue.

6

Hidradenoma papilliferum: Lining.

Luminal layer of columnar or cuboidal cells.

Basal layer of myoepithelial cells.

7

Herpes viral infection: Histology (4).

"Multinucleation, margination, and molding."

Ground-glass intranuclear inclusions.

Ballooning degeneration of keratinocytes.

Epidermal necrosis and vesiculation.

8

Molluscum contagiosum: Cause.

A DNA virus.

9

Vulvar condyloma: Types of HPV.

6, 11.

10

Vulvar condyloma: Grading.

Mitotic figures and cytologic atypia:

− Confined to the lower third: VIN 1.
− Present in the middle third: VIN 2.

11

Vulvar condyloma acuminatum: Behavior (2).

Most lesions regress spontaneously.

Some have progressed to high-grade dysplasia or to carcinoma.

12

Lichen sclerosus: Relation to squamous-cell carcinoma.

LS is not considered a precancerous condition.

SCC arises in up to 5% of cases of LS in postmenopausal women.

13

Lichen sclerosus: Treatment.

Topical corticosteroids.

14

Lichen simplex chronicus vs. squamous-cell hyperplasia.

Squamous-cell hyperplasia is like LSC but without the dermal changes.

15

Lichen simplex chronicus: Relation to squamous-cell carcinoma.

None known.

16

The vulvo-gingival syndrome.

Lichen planus involving vulva, vagina, and oral mucosa.

17

Lichen planus: Histology of advanced disease (2).

Epidermal atrophy.

Postinflammatory hypopigmentation.

18

Cyst of Bartholin's duct: Cause.

Obstruction of the duct.

19

Cyst of Bartholin's duct:

A. Lining.
B. Contents.

A. Squamous, transitional, or cuboidal.

B. Secretions but no laminated keratin.

19

Lower Anogenital Squamous Terminology (LAST) terms for ___.

A. Condyloma acuminatum.
B. Bowenoid papulosis.

A. LSIL.

B. HSIL.

20

Vulvar erythroplasia of Queyrat: Grade.

VIN 3.

21

Squamous-cell carcinoma of the vulva: Epidemiology.

Young women who smoke and have HPV-associated lesion.

Postmenopausal women without evidence of HPV.

22

Superficially invasive SCC of the vulva: Criteria (2).

Depth of invasion of more than 1 mm (measured from the base of the nearest dermal papilla).

Less than 2 cm in diameter.

23

Invasive SCC of the vulva: Criterion.

Depth of invasion is than 1 mm.

24

Invasive SCC of the vulva: Grading.

Grade 1: No undifferentiated cells; keratin pearls.

Grade 2: Less than half of cells are undifferentiated.

Grade 3: More than half of cells are undifferentiated.

25

Verrucous carcinoma of the vulva: Synonym.

Giant condyloma of Buschke and Löwenstein.

26

Warty carcinoma of the vulva:

A. Synonym.
B. Silhouette.

A. Condylomatous carcinoma.

B. Papillary and exophytic.

27

Warty carcinoma of the vulva: Histology (3).

Fibrovascular fronds.

Many koilocytes.

Irregularly outlined nests of invasive tumor at the base.

28

Squamous-cell carcinoma of the vulva: Important histologic prognostic factors (4).

Dimensions of tumor
− Thickness.
− Depth of invasion.
− Diameter.

Invasion of lymphatic spaces.

29

Squamous-cell carcinoma of the vulva: Relation of depth of invasive to nodal status.

Depth of invasion greater than 1 mm imparts a significantly greater risk of involvement of inguinal lymph nodes.