Final Exam Misc. Flashcards

1
Q

secondary adverse reaction

A

additional to the desired effect

-eg. antihistamines make you drowsy

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2
Q

cytotoxic effect

A
  • attack and lysis of the cell that has the drug -on it

- causes drug-induced hemolytic anemia

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3
Q

serum sickness

A

caused by body reacting to antibodies combining with the drug
-lyme disease

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4
Q

delayed reaction

A

time-lapse between taking the drug and adverse reactions

-eg. poison ivy

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5
Q

labs for antifungals

A

ALT and AST… liver labs

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6
Q

causes and s/s of disulfiram-like reactions

A
  • disulfiram = Antabuse
  • taking metronidazole with alcohol
  • s/s: n/v, flushing, tachy, shortness of breath… problem with CO until proven otherwise
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7
Q

problem with any antineoplastic agent that starts with a “d”, like “doxyrubicin”

A

bad effects on the heart

  • check for hypertrophy
  • causes mouth sores
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8
Q

SIADH

A
  • syndrome of inappropriate ADH
  • too much ADH causes extreme fluid retention
  • patient will need a diuretic
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9
Q

how to draw up insulin

A
  1. put air in the intermediate
  2. put air in the rapid
  3. draw up the rapid
  4. draw up the intermediate
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10
Q

most dangerous side effect of SSRIs

A

fever- hypertensive crisis

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11
Q

where are alpha 1 receptors located

A

eyes, salivary glands, GI/ GU sphincters, arterioles

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12
Q

where are alpha 2 receptors located?

A

smooth muscle, NMJ synapse

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13
Q

where are beta 1 receptors located?

A

heart, brain, kidneys

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14
Q

where are beta 2 receptors located?

A

smooth muscle, bronchioles, liver, uterus

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15
Q

side effects of all beta blockers

A

problems with heart and lungs

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16
Q

treating angina

A

MONA- morphine, oxygen, nitroglycerin, aspirin

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17
Q

drugs that treat problems with afterload

A

HMG-CoA reductase inhibitors

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18
Q

antidote to warfarin

19
Q

labs for warfarin

A

PT and INR

20
Q

antidote to enoxaprin

A

protamine sulfate

21
Q

labs for enoxaprin and heparin

22
Q

definition of infertility

A

diagnosed after at least one year of regular unprotected intercourse

23
Q

assessments for clomiphene

A
  • has it been long enough to consider the pt infertile?

- is there ovarian function? (test by checking estradiol levels in the urine)

24
Q

clomiphene is known for…

A
  • having a baby that is anencephalic
  • gastroschisis- bowel is outside the body cavity when they are born
  • having a litter
25
where do osmotic diuretics work
before the glomerulus
26
where do carbonic anhydrase inhibitors work?
descending loop of Henle
27
where do loop diuretics work?
in the ascending loop of Henle
28
where do potassium-sparing diuretics work?
in the DCT
29
where do thiazide diuretics work?
in the DCT
30
s/s of UTI... bladder vs kidney infection
- bladder: urinary frequency and urgency, burning on urination - kidney: chills, fever, flank pain and tenderness (associated with pyelonephritis)
31
- what chemotherapeutic agent causes hemorrhagic cystitis? | - what protects against it?
- cyclophosphamide (Cytoxan) | - Mesna
32
location of M1 receptors
ENS and CNS
33
location of M2 receptors
heart
34
location of M3 receptors
eyes, exocrine glands, lungs, GI/GU
35
Anticholinergic 4 aunties
antipsychotics, antihistamines, antidepressants, antiparkinsons
36
rebound acidity
chronic use of antacids will tell the stomach to produce more acid, then you take more meds, which makes the stomach think its needs to produce even more, etc..
37
teaching for pts on oral contraceptives
- no protection against STDs - 1 pill missed: take 2 the next morning - 2 pills missed: take 2 for the next 2 mornings - 3 pills missed: all hope is lost and you have to start a new pack 7 days after the last pill was taken
38
rapid acting insulin
aspart (Novolog) | lispro (Humalog)
39
short acting insulin
regular (Humulin R)
40
intermediate acting insulin
NPH (Humulin N)
41
long acting insulin
glargine (Lantus)
42
assessments for levothyroxin
- s/e: insomnia, weight loss, heat intolerance | - therapeutic effects: decline in TSH levels
43
diabetes insipidus
- polyuria (pee a lot of dilute urine) and polydipsia (very thirsty) - DO NOT experience polyphasia (starving) like with DM - can be a problem with pituitary gland - opposite of SIADH