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Nutrition > Folate > Flashcards

Flashcards in Folate Deck (27):
1

is it a trace element, vitamin, or mineral? Folate

B vitamin

2

what are its three forms? Folate

food, coenzyme, excreted from liver into bile then reabsorbed by intestine

3

what are the details of its form in food? Folate

not biologically active, bound to glutamates

4

which form in food is preferred for absorption? Folate

monoglutamate

5

which is the storage form in food? Folate

polyglutamate

6

what are the two coenzyme forms? Folate

tetrahydrofolate (THF), dihydrofolate (DHF)

7

what happens when the intestinal cells are damaged? Folate

it hinders absorption

8

what are its three functions? Folate

carrier of one carbon compounds, DNA and red blood cell formation

9

what are the three different carbon compounds it carries? Folate

methanol, formaldehyde, formic acid

10

what happens with its function in DNA and red blood cell formation? Folate

protein synthesis and cell division

11

what are the three deficiency symptoms? Folate

macrocytic anemia, smooth tongue, changes in intestinal cells

12

what is the deficiency symptom macrocytic anemia? Folate

arrested development of rbc: nuclei, large, irregular shape

13

what happens with the deficiency symptom of changes in intestinal cells? Folate

diarrhea

14

what are the five predisposing factors of deficiency? Folate

inadequate intake, impaired absorption, enhanced cell multiplication (cancer), drugs, smoking

15

what are the three things that happens with a deficiency in pregnancy? Folate

neural tube defects in the 1st 3 weeks, spina bifida, anencephaly

16

what happens with a neural tube defect? Folate

lots of urinating and vomiting

17

what is spina bifida? Folate

split or open spine

18

what is anencephaly? Folate

no brain

19

how can a deficiency in pregnancy be prevented? Folate

supplements 1 month prior and 1st trimester

20

what are its dual roles in cancer? Folate

low intake protects against early cancinogenesis; high intake promotes advanced carcinogenesis

21

what is the recommended daily intake for adults? Folate

400 micro grams

22

whats the upper limit for adults? Folate

1000 micro grams

23

whats the recommended daily intake for pregnancy? Folate

600 micro grams

24

whats the upper limit in pregnancy? Folate

800 micro grams

25

what are the three toxicity effects? Folate

masks deficiency of b12, changes to brain leading to autism and metabolic syndrome, increase risk of malaria in children

26

what are the seven food sources? Folate

leafy green vegetables, legumes, okra, asparagus, orange, strawberries, enriched grains

27

is the amount limited in enriched grains? if so why? Folate

limited to not mask b12 deficiency