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fung Flashcards

1
Q

all of systemic mycoses cause

A

pneumoniae

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2
Q

all sysetmic mycosis caused by

A

dimorphic fungi

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3
Q

what is dimorphic fungi

A

cold (20C) = mold

heat (37C) = yeast

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4
Q

exception to dimoprhic fungi

A

coccidiodes

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5
Q

why is coccidiodes exception to dimorphic fungi

A

it is a spherule (not yeast) in tissue

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6
Q

Treatmetn for local infection of mycosese

A

fluconazole, itraconazole

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7
Q

treatment for systemic infection of mycoses

A

amphotericin B

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8
Q

located in mississippi and ohio river valleys

A

histoplasmosis

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9
Q

small ovoid bodies within a macropahge

A

histoplasmosis

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10
Q

macrophage filled with histoplasma (smaller than rBC’)

A

histoplasmosis

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11
Q

palatal/tongue ulcers, splenomegaly

A

histoplasmosis

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12
Q

bird or bat droppings in mississisppi

A

histopalasmosi

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13
Q

diagnose histoplasmosis via

A

urine/serum antigen

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14
Q

histoplasmsos is transmitted thorough

A

inhalation; converts to yeast form in lungs; replicates within phagosome of macs

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15
Q

ulcerated lesions on tongue

A

histoplasmosis

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16
Q

impaired immunity for histoplasmsosi

A

AIDS; at risk for dissemination through RES system due to organisms affinity for mononuclear phagocytic cells

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17
Q

located in easter and central us; ohio mississippi river valley, GREAT LAKES REGION

A

blastomycosis

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18
Q

broad based budding

A

blastomycoses

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19
Q

same size as RBC

A

blastomycosis

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20
Q

inflammatory lung diseaes, can disseminate to skin/bone. on skin is papular or pustular lesions

A

blastomycoses

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21
Q

verrucous skin lesions that can stimulate SCC

A

blastomycoses

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22
Q

forms granulomatous nodules

A

blastomycoses

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23
Q

immunocompormised pt’s in blastomycoses

A

bone pain (lytic lesions), skin lesions, systemic symptoms, lung involvement

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24
Q

biopsy of blastomycoses

A

large round yeasts w doubly refractible wall and single broad based budd

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25
southwestern US, california
coccidiomycosis
26
northern mexico, central south america, san joaquin valley
coccidiomycosis
27
thick walled spherule
coccidiomycosis
28
spherule filled with endospores of
coccidiodes
29
mycoses: erythema nodosum (desert bumps) or multiforme arthalgias (desert rheumatism)
coccidiomycois
30
coccidioodcymocis disseminates to skin/bones and causes meningitis
True
31
located in latin america ; central + south america
paracoccidiodomycosis
32
budding yeast with captain wheel formation (much larger than RBC)
paracoccidiomycosis
33
multiple budding blastocondia
paracoccidiomycosis
34
both replicate within macrophages
blastomcyosis and cocidiomycosis
35
forms pseudohyphae and budding yeasts at 20C
candida
36
germ tubes formed at 37
candida
37
oral, esophageal thrus in immunocompromised
candida
38
vulvovaginits, diaper rash, endocarditis,
candida
39
normal inhabitant of GI tract (including oral cavity, skin, vagina, intestin
candida
40
can be easily scraped off buccal mucosa
thrush
41
most cases of thrus due to
disruptions in normal flora due to antibiotics;
42
young healthy individuals with thrush:test for
HIV
43
superficial candida use associated with
antibitoic use, corticosteriod, DM , HIV, immunosuppressing
44
disseminated candidias especially in
neutropenic pt's
45
white psuedomembrane candidia
esophagitis
46
uncommon resp infection in CA
CANDIDA
47
septate hyphae that branch at 45
aspergillus fumigatus
48
Acute angle v shaped branching
aspergillius
49
produces radiating chains at end of conidiophore
aspergillus
50
aspergillus is inhaled by
air
51
coloinizes old lung cavities to form fungal ball
aspergillus (aspergilloma
52
symptoms of aspergilloma:
cough dyspnea hemotypsis
53
assoc with HCC
aflatoxin produced by aspergillus
54
radioopaque structure that shifts when pt changes posisiont
aspergillus
55
MOLD FORM ONLY
aspergillus
56
monomorphic fungus
aspergillus
57
angioinvasive pneumonia means
fever pleuritic pain, chest pain, hemotypissi
58
angioinvasive pneumonia seen in
aspergillus
59
hypersenstivity response associated with asthma and CF; may cause bronchiectasis and eosinophilia
allergic bronchopulmonary aspergillosis
60
invasive aspergillosis seen in
hiv pt's cd<50. fever, cough , sob, pul infiltrate
61
serologic testing diagnoses abpa: see what
increase ige, eosinophils, ab
62
aspergilloma affects where in lungs
upper lobes
63
only exist in mold form
rhizosups and aspergillosis
64
Pt's receivin parenteral nutrition thorugh central venous catherher have a high risk for
candidemia (sepsis)
65
CNS aspergillosis
abscess (single ring enhancing lesioN)
66
narrow budding
cryptococcus neoformans
67
heavily encapsulated yeast, )polysaccharide capsuel
cryptococcus neoformans
68
only exist in yeast form
cryptococcus neoformans
69
found in soil, pigeon droppings
cryptococcus neoformans
70
culture on sabouraud agar
cryptococcus neoformans
71
cryptococcus neofrmans is highlited with
india ink of CSF and muscarimine
72
describe india ink :
clear halo due to thick polysaccharide capsule
73
describe muscarimine
red inner capsuel
74
what detects polysaccharide capsular antigen in cryptoccous
latex agglutination test
75
manifestsaions of cryptococcus neofromans
cryptoccosis, cryptococcal meningits, cryptococcal encephalitis
76
what type of lesions seen in brain of cryptococcal encephalitiss
soap bubble lesions
77
methenamine silver stain in cryptoccus neofromans show
round cells w narrow based buds
78
irregular broad nonseptate hyphae branching at wide angles
mucor and rhizopus
79
DKA and neutropenic patients
mucormycosis
80
mucor and rhizpus proliferate in
blood vessel walls , penetrate cribiform plate, enter ribbon
81
broad ribbon like nonseptate hyphae w rt angle brnaching
mucor and rhizpus
82
manifestaions of mucor and rhizpus
rhinocerebral , frontal lobe abscess, cavernous sinus thrombosis;
83
What type of symptosm of mucor and rhizpus
headache, facial pain, black necrotic eschar on face (nasal cavity; may have cranial nerve involvement
84
facial pain, sinus infection , headache, nasal eschar
mucormycosis
85
recurring fleeting infitlartes on chest imaging;
abpa
86
lung infection w lung granulomas; fever, pleuritic chest pain, hemotypisis. predilection for blood vessels
asperigllus (invasive)
87
CSF of cryptootcocsu
low glucose, increase protein, mild ploecytis w predominance of lymphocytes; ELEVATED OPENING PRESSURES ON LP due to increase vascular permeability

Microbiology (13 decks)

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