GA Flashcards
1
Q
What has a low blood:gas partition coefficient?
A
NO
2
Q
Which kind of BGPC needs a loading dose?
A
High
3
Q
Which BGPC needs higher partial pressure for anaesthesia?
A
Low
4
Q
Which BGPC has significant fat trickle?
A
High
5
Q
Which beta3 GABA mutation reduces efficacy?
A
TM2 N265M
6
Q
Which GABA mutation blocks halothane and isoflurane?
A
S270W in alpha subunit
7
Q
How do halothane and enflurane work?
A
Glycine receptor potentiation
8
Q
What do halothane and enflurance potentiate?
A
TASK3 2PK+
9
Q
Which mutation inhibits halothane and isoflurane?
A
M159A
10
Q
WHich knockout mice are less sensitive to halothane?
A
TREK1
11
Q
Which mutations reduce inhibition of teh NMDA receptor?
A
TM3/4
