Gastric Digestion and Disease Flashcards Preview

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Flashcards in Gastric Digestion and Disease Deck (35)
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31

Causes of Peptic Ulcer Disease (stomach or duodenum)

Mainly H.pylori and aspirin and NSAIDs

32

How did they initially treat peptic ulcers

gastrectomy (remove antrum)
Vagotomy (part of vagus nerve)
Pyloroplasty: cut and resuture pylorus

33

Symptoms of peptic ulcers

non-specific epigastric pain
bleeding
perforation
obstruction due to scarring/fibrosis

34

2 main types of Gastric Cancer

1) Intestinal : well differentiated and cells arranged in a tubular/glandular pattern
2) Diffuse: Poorly differentiated cells, lack of glandular formation. Can infiltrate gastric wall

35

How does H.pylori affect gastric cancer

Can produce widespread inflammation of gastric mucosa and destruction of parietal cells > low acid (achlorydria) > bacterial overgrowth > carcinogens