Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm 1 > Gastro part 1 > Flashcards

Gastro part 1 Flashcards

1
Q

What is a strict contraindication to using any laxative

A

bowel obstruction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does a laxative do

A

Allows for increased movement of stool through the bowels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What drug class is metamucil

A

fiber laxative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the MOA of metamucil

A

Adds bulk to stool and well as absorbing fluid into the feces to soften the stool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which form of metamucil contains gluten

A

The wafers (which of course are tastier than the drink powder)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What drug class is Docusate (colace)

A

stool softener

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the MOA of docusate

A

anionic surfactant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What drug type cause constipation

A

narcotics of all types. The mau receptor sites that they act on are responsible for peristalsis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What drug class is milk of magnesia

A

osmotic laxative, antacid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what drug class is Bisacodyl/ Dulcolax

A

stimulant laxative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what drug class is loperamide (imodium)

A

antidiarrheal (analog of meperidine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the MOA of loperamide (imodium)

A

Diminished peristalsis due to activation of opiate receptors in GI tract. Loperamide is an opioid receptor agonist and acts on the μ-opioid receptors in the myenteric plexus within the large intestines. It does not affect the central nervous system like other opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the indications of loperamide (imodium)

A

acute diarrhea and management of chronic bowel disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What drug class is diphenoxylate with atropine (lomotil)

A

antidiarrheal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the MOA of lomotil

A

Combination of morphine analog and acetylcholine inhibitor results in diminished peristalsis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What drug class is meclizine (anti vert)

A

antiemetic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the MOA of meclizine (antivert)

A

H1 histamine blocker

18
Q

What are the side effects of meclizine

A

drowsiness, dizziness, dry mouth, urinary retention

19
Q

What drug class is metoclopramide (reglan)

A

antiemetic and a prokinetic

20
Q

What are the indications of metoclopramide (reglan)

A

gastroparesis, mild to moderate nausea, GERD

21
Q

What is the MOA of metoclopramide (reglan)

A

Dopamine 2 blocker and mixed serotonin 3 antagonist/serotonin 4 agonist

22
Q

what drug class is ondansetron (zofran)

A

antiemetic

23
Q

What is the MOA of ondansetron (zofran)

A

Blockade of serotonin (5HT3) receptor sites results in signifigant anti-nausea effect

24
Q

What are in the indications of ondansetron

A

given prophylaxically for chemo therapy

25
Q

What drug class is syrup of ipecac

A

emetic

26
Q

what are the major causes of PUD

A

H. pylori, NSAID and/or aspirin use, severe stress

27
Q

What drug class is calcium carbonate (tums)

A

antacid

28
Q

What is the MOA of calcium carbonate

A

neutralization of stomach acid, reducing mucosal irritation

29
Q

What are the side effects of calcium carbonate use

A

Constipation. may block nutrient absorption and inhibit protection against ingested microbes

30
Q

What drug class is ranitidine (zantac)

A

H2 histamines receptor antagonist

31
Q

What are the indications for ranitidine (zantac)

A

Gastritis, GERD, PUD

32
Q

What are some side effects of ranitidine (greater if given IV)

A

altered mental status, dizziness

33
Q

What are the risks of being on a PPI or H2 blocker

A

Your stomach pH is higher so that it doesn’t kill ingested pathogens, and decreases protein digestion, nutrient absorption. Greater risk for pneumonia and C. diff

34
Q

what drug class is omeprazole (prilosec)

A

proton pump inhibitor

35
Q

What is the MOA of omeprazole

A

Inhibits H+/K+ ATPase pump of parietal cells thus reducing acid secretion

36
Q

What are the indications of omeprazole

A

gastritis, GERD, PUD

37
Q

What is the most potent type of gastritis drug

A

PPI’s

38
Q

What drug class is esomeprazole (nexium)

A

It is the enaniomer of omeprazole, and identical in action

39
Q

How do you treat PUD due to H. pylori

A

triple therapy: 2 abx and a PPI

40
Q

What antibiotics can be used for H. pylori

A

amoxicillin, erythromycin, clarithormycin, tetracycline, metronidazole (Not zithro)

Pharm 1 (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions