General Medications Flashcards

1
Q

what is breo eliptica?

A

fluticasone furoate and vilanterol

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2
Q

Allopurinol HS reaction gene that we test for is what?

A

HLAB5801

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3
Q

name some anti-cholinergic drugs

A

benztropine and benzhexol
prochlorperazine
hyoscine hydrobromide.
sedating antihistamines (eg promethazine, doxylamine)
drugs for bladder overactivity (eg oxybutynin, tolterodine)
some antipsychotics
tricyclic antidepressants (eg amitriptyline)

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4
Q

what are the drugs commonly used to treat PD?

A

levodopa
dopamine agonists- bromocriptine, pramipexole
Mao-B inhibitors
muscarinic Ach receptor antagonists

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5
Q

when is viagra contraindicated?

A
  1. severe cardiovascular disease
  2. recent MI
  3. concurrent use of nitrates
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6
Q

what is sinemet?

A

levodopa + carbidopa

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7
Q

what is stemitil?

A

prochlorperazine

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8
Q

Key SE of ace inhibitors

A

cough, renal impairment, hyperkalemia, hypotension

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9
Q

Key SE of calcium channel blockers

A

constipation, peripheral oedema

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10
Q

what drug can we sometimes use to prevent recurrent/chronic UTIs? what is preferred?

A

hexamine hippurate can sometimes be used. It acidifies the urine by conversion into ammonia, which is bacteriocidal. however evidence is not good for this drug, and often it is ineffective in renal/liver impairment. It is also contraindicated for gout as it may precipitate urate crystals.

preferred options- cranberry, vitamin C, regular fluids (prevent dehydration)

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11
Q

a patient comes in with known CCF requesting pain management for joint pain. Would you prescribe a NSAID?

A

no!

it can cause salt and fluid retention, and also contribute to renal impairment. This can push the patient into APO

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12
Q

what is ditropan?

A

oxybutynin

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13
Q

common SE of ARBs?

A

dizziness, headache, hyperkalaemia

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14
Q

what is the common theme between metoclopramide, domperidone, haloperidol and prochlorperazine?

A

all dopamine antagonist anti-emetics

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15
Q

why might domperidone be a better choice for PD patients?

A

doesn’t cross the BBB as readily so EPSE are rare

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16
Q

what is buscopan?

A

hyoscine butylbromide- smooth muscle relaxant for GI spasms

17
Q

what are the five systems in the body which feed into the vomiting centre and how might they mediate emesis?

A

biochemical changes/drugs–> Chemoreceptor trigger zone
ICP–> pressure receptors
Movement–> Vestibular nucleus
anxiety –> Cerebral cortex
Gastric stasis/BO/constipation–> Gastrointestinal tract

18
Q

what do we mean by ‘stoss dose’ for vitamin D?

A

a one off highly concentrated dose of vitamin D for vitamin d deficiency

19
Q

how do we advise women who take transexamic acid for their heavy periods?

A

start 2 days before the period, and take daily during the period.

20
Q

what is synaral?

A

GNRH agonist

21
Q

when is transexamic acid contraindicated?

A

if the woman has a history of thromboembolic disease