GI Bug Tx Flashcards

1
Q

What drug is first line for CDI Tx?

A

Vancomycin

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2
Q

What drug is used for recurrent CDI?

A

Fidaxomicin

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3
Q

Which drugs do you give for E. Histolytica to Tx the invading microbes?

A

Metronidazole, Tinidazole

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4
Q

Which drugs do you give for E. Histolytica to Tx the intraluminal microbes?

A

Paromomycin, Lodoquinol

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5
Q

Which drug do you give for Giardia Tx?

A

Nitazoxanide

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6
Q

What are the SE of Nitazoxanide?

A

Yellow eyes, bright yellow urine

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7
Q

When would you give a drug for Crypto Parvum Tx?

A

In immunosuppressed pts

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8
Q

What drug do you give for Crypto Parvum Tx?

A

Nitazoxanide

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9
Q

Do you continue or discontinue the immunosuppressive drug when treating for Crypto Parvum?

A

Continue if HIV, discontinue if anything else

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10
Q

How is Necator Americanus/Ancylostoma Duodenale excreted?

A

Eggs

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11
Q

How is Ascaris Lumbricoides excreted?

A

Eggs

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12
Q

How is Strongyloides Stercoralis excreted?

A

Larvae

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13
Q

How is Trichuris Trichiura excreted?

A

Eggs

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14
Q

How is Enterobius Vermicularis excreted?

A

Eggs deposited in perianal region

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15
Q

What is the primary drug for Necator Americanus and Ancyclostoma Duodenal Tx?

A

Albendazole

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16
Q

What are the primary drugs for Ascaris Lumbricoides Tx?

A

Albendazole, Mebendazole

17
Q

What is the primary drug for Stronguyloides Stercoralis Tx?

A

Ivermectin

18
Q

What is the primary drug for Trichuris Trichiura Tx?

A

Mebendazole

19
Q

What are the primary drugs for Enterobius Vermicularis Tx?

A

Albendazole, Mebendazole, Pyrantel Pamoate

20
Q

What is the MOA of Albendazole, Mebendazole, and Thiabendazole?

A

Inhibit microtubule synthesis

21
Q

What is the MOA of Ivermectin?

A

Stimulates GABA in peripheral neurons

22
Q

What is the MOA of Pyrantel Pamoate?

A

Stimulates Ach and inhibits AchE at NMJ

23
Q

What is excreted in the feces from Schistosomas?

24
Q

What is excreted in the feces from Taenia Solium/Saginata?

A

Proglottids

25
What is excreted in the feces from Diphyllobothrium Latum?
Proglottids
26
What drug is used to Tx Schistosomas?
Praziquantel
27
What drug is used to Tx Taenia Solium/Saginata?
Praziquantel
28
What drug is used to Tx Diphyllobothrium Latum?
Niclosamide
29
What drug is used to Tx Echinococcus Granulosus?
Praziquantel
30
What is the MOA of Praziquantel?
Increase Ca permeability of cell membranes causing paraylsis