Hepatitis Tx Flashcards Preview

Zak, GI 2 > Hepatitis Tx > Flashcards

Flashcards in Hepatitis Tx Deck (8):
1

What is the MOA of INF-a drugs for HBV?

Inhibit viral DNA integration into host DNA via ZAP

2

What is the MOA of Nucleoside/nucleotide drugs?

Inhibit reverse transcriptase and DNA polymerase from the virus

3

Which drug would you use for HBV first line that is easy on the kidney?

Entecavir

4

Which drug would you use for wild-type HBV first line that causes proximal renal tubule disease?

Tenofovir

5

Which HCV drug inhibits NS5B?

Sofosbuvir

6

Which HCV drugs inhibits NS5A?

Ledipasvir, Elbasvir, Velpatasvir

7

What is the Genotype 1 drug regimen for HCV Tx?

Ledipasvir + Sofosbuvir

8

What are the Genotype 2 drug regimens for HCV Tx?

Velpatasvir + Sofosbuvir
Elbasvir + Grazoprevir