Antacids/Anti-Ulcer Tx Flashcards Preview

Zak, GI 2 > Antacids/Anti-Ulcer Tx > Flashcards

Flashcards in Antacids/Anti-Ulcer Tx Deck (15):
1

What is MOA of Simethicone?

Creates gas by decreasing surface tension

2

Which H2R antagonist inhibits T binding to androgen receptors?

Cimetidine

3

Which H2R antagonist is acceptable for pregnancy?

Ranitidine

4

Which PPI is acceptable for pregnancy?

Lansoprazole

5

What is the major SE of PPI's that warrants immediately stopping their use?

CDAD

6

What is the MOA of Sucralfate?

Creates viscous band-aid over ulcer and stimulates mucous secretion

7

When is Sucralfate contraindicated?

Renal disease

8

When are PGE1 analogs mostly used?

NSAID-induced gastric ulcers

9

What is the MOA of Bismuth Subsalycilate?

Antimicrobial agent

10

When is Bismuth Subsalycilate absolutely contraindicated?

GI bleeding, salicylate hypersensitivity

11

What is the 14 day Tx regimen for H. Pylori?

2 ABX (clarithro, amoxi) and a PPI (or H2 antag)

12

What is the 10 day Tx regimen for H. Pylori?

Tetra, Metro, PPI, Bismuth Subsalicylate

13

If a pt has H. Pylori and a PCN allergy, which ABX do you sub in?

Metro

14

If a pt has H. Pylori and metro resistance, which ABX do you sub in?

Tetra

15

If a pt has H. Pylori and clarithro resistance, which ABX do you sub in?

Amoxi or Tetra