Glomerulonephritis

Question 1

Typically presents with Nephritic picture

Answer 1

Rapidly progressive GN
(e.g. Goodpasture’s, ANCA +ve vasculitis)

IgA nephropathy

Alport syndrome

Question 2

Mixed nephrotic/nephritic picture

Answer 2

Diffuse proliferative glomerulonephritis
- usually post-strep in child

Membranoproliferative glomerulonephritis
type 1: cryoglobulinaemia, Hep C
type 2: partial lipodystrophy

Question 3

Typically presents with nephrotic picture

Answer 3

Minimal change
Membranous
FSGS
Amyloid
Diabetic nephropathy

Question 4

Describe a nephritic presentation

Answer 4

Haematuria
Hypertension

Question 5

Describe a nephrotic presentation

Answer 5

Proteinuria
oedema

Question 6

This type of nephropathy is typically seen in young adults. It presents with haematuria following an URTI

Answer 6

IgA nephropathy

Question 7

Child with nephrotic syndrome

Answer 7

Minimal change disease

Question 8

Causes of minimal change GN

Answer 8

Hodgkin’s
NSAIDs

Question 9

Patients with minimal change nephropathy have a good response to steroids. TRUE/FALSE?

Answer 9

TRUE

Question 10

3 common cause of membranous glomerulonephritis

Answer 10

• infections
• rheumatoid drugs
• malignancy

Question 11

Describe the prognosis in membranous glomerulonephritis

Answer 11

1/3 resolve
1/3 respond to cytotoxics
1/3 develop CKD

Question 12

Common causes of FSGS

Answer 12

idiopathic
secondary to HIV OR heroin

Question 13

Glomerulonephritides with low complement levels

Answer 13

post-strep. GN
mesangiocapillary GN

Question 14

Disorders which are also associated with glomerulonephritis and low complement levels

Answer 14

subacute bacterial endocarditis
SLE