GLP-1

Question 1

SE of GLP-1s

Answer 1

• Decreased appetite
• Weight loss
• Injection Reaction
• GI disturbances
• Acute pancreatitis
• RARE: ANGIOEDMEA

Question 2

GLP-1 AND CONTRACEPTION

Answer 2

• MUST BE DURING AND 2 MONTHS AFTER
• May reduce the effectiveness of oral contraceptives
  MHRA JUNE 2025:

Question 3

CI of GLP-1

Answer 3

• hx of pancreatitis,
• Severe gI disease
• Family hx of medullary thyroid carcinoma
• DKA

Question 4

Important safety info for GLP-1

Answer 4

1) Risk of DKA with insulin reduction- insulin dose reductions should be gradual
2) Risk of gall bladder disease and pancreatitis
3) Potential for misuse