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Flashcards in GU Infections Deck (25):
1

what 2 common GU infections are tested for simultaneously and how?

chlamydia and gonorrhea; voided urine PCR probe

2

dx: creamy purulent discharge from penis/vagina

neisseria gonorrhoeae

3

treatment for neisseria gonorrhoeae infection

ceftriaxone

4

dx: infection causing pelvic inflammatory disease and conjunctivitis

chlamydia trachomatis

5

what form of chlamydia trachomatis is infectious? is this form metabolically inactive or active?

elementary body (Enfectious); metabolically inactive

6

treatment for chlamydia trachomatis infection

azithromycin and doxycycline

7

treatment for trichomonas vaginalis infection

metronidazole

8

treatment for ureaplasma

erythromycin and doxycycline

9

ddx: painful genital lesions

herpes, chancroid (haemophilus ducreyi), lymphogranuloma venereum

10

ddx: non-painful genital lesions

syphilis, molluscum, genital wart

11

dx: painful penile, vulvar, or cervical vesicles and ulcers

HSV-2, less commonly HSV-1

12

dx: painful ulcerated lesion with lymphadenopathy, culture shows pleomorphic gram negative rods

haemophilus ducreyi

13

haemophilus ducreyi: what disease does it cause, what is it, treatment

chancroid; pleomorphic gram negative rod; azithromycin, ceftriaxone, ciprofloxacin

14

causative agent of syphilis

treponema pallidum

15

dx: painless chancre

primary syphilis (treponema pallidum)

16

describe the primary, secondary, and tertiary stages of syphilis (treponema pallidum)

primary: painless chancre at inoculation site, highly infectious
secondary: disseminated disease with constitutional symptoms, maculopapular rash (including palms and soles), condylomata lata (smooth, moist, painless, wart-like white lesions on genitals)
tertiary: chronic granulomas (gummas), aortitis, neurosyphilis, Argyll Robertson pupil (constrict with accommodation but not reactive to light), due to immune system-driven damage to multiple organs

17

syphilis (treponema pallidum): treatment

penicillin G

18

dx: flesh-colored papules with central umbilication

molluscum contagiosum

19

molluscum contagiosum: what is it, life cycle, histology

very large dsDNA virus in poxvirus family; single life cycle of lytic replication; histology shows molluscum bodies (large eosinophilic inclusions in the cytoplasm = viral "factories")

20

HPV: what is it, what does initial infection require?

dsDNA virus; access to basal epithelial layer via skin damage --> replicates in upper layers of epithelium --> warts

21

when does HPV cause cancer?

upon accidental integration of broken viral DNA into host genome

22

dx: clue cells (vaginal epithelial cells with shaggy borders) seen under microscope

gardnerella vaginalis

23

normal pH of vagina

4.5

24

gardnerella vaginalis: what is it, treatment

pleomorphic gram variable rod, part of normal vaginal flora; metronidazole or clindamycin

25

treatment for vaginal candidiasis

fluconazole