Metabolic Syndrome and Menopause Flashcards Preview

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Flashcards in Metabolic Syndrome and Menopause Deck (10):
1

PCOS: hyperinsulinemia _____ SHBG and results in ____ free testosterone

decreases; higher

2

describe abnormal lipids in PCOS patients

elevated TG, low HDL

3

PCOS can cause increased risk of ______ secondary to _______

endometrial cancer; unopposed estrogen from repeated anovulatory cycles

4

mechanism of oral contraceptive pills used to treat PCOS

suppress ovarian androgen secretion by suppression of gonadotropins, increases SHBG, decreases free testosterone, regulates menses and provides adequate progestin to protect endometrial lining (lowers risk for endometrial hyperplasia)

5

what is perimenopause?

transition phase before menopause that can last 6 years or more and ends 1 year after the final menstrual period

6

age cutoff for premature menopause

40

7

consequences of estrogen deficiency in postmenopausal years

increased risk of osteoporosis, diabetes, heart disease, skin changes

8

treatment for female patient above 40 with moderate to severe dyspareunia (painful intercourse)

ospemifine (SERM)

9

contraindications for raloxifene

patients who are experiencing vasomotor symptoms of menopause (hot flashes); may exacerbate them

10

3 common progestins

medroxyprogesterone, northindrone, prometrium