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Flashcards in Hematology Review Deck (37)
1

What is the normal range for MCV?

80-100

2

What is the most common microcytic anemia?

Iron deficiency anemia

3

Would anemia of chronic disease most likely be macrocytic, normocytic or microcytic?

Normocytic

4

What two main causes should you be thinking of in a macrocytic anemia?

Malnutrition and severe blood loss

5

Does an increase in reticulocytes indicate a decrease or an increase in RBC production?

An increase, reticulocytes are newly released "baby" RBC's.

6

Auer rods a most commonly associated with what disease?

Acute Myeloid Leukemia

7

What molecule binds iron in the blood stream?

Transferrin

8

What does koilonychia refer to?

Spoon shaped nails. This may be found in microcytic anemia.

9

Will the serum ferritin be high or low in a patient with iron deficient anemia?

It will almost always be low

10

A low retic count and a normal serum ferritin should make you think of what diagnosis?

Anemia of chronic disease

11

Under normal conditions at what hemoglobin level would you begin to consider a transfusion?

8

12

Asplenism secondary to sickle cell disease increases a patient's risk for what type of infections?

Capsulated organisms like Strep pneumo and H. flu.

13

An African American teenager presents with avascular necrosis of the his right femoral head. What is the most likely diagnosis?

Sickle Cell disease

14

How do you treat a sickle cell crisis?

Fluids, oxygen, pain medication, transfusion may be necessary.

15

Will unconjugated bilirubin be high or low in a patient with sickle cell disease?

High

16

Which anemia should you think of if you see the term Howell-Jolly bodies?

Sickle cell due to the functional asplenia, but it may also show up in folic acid deficiency.

17

G6PD deficiency follows what pattern of inheritance?

X- linked

18

List the three diagnosis you should be thinking of if a question includes Heinz bodies.

G6PD deficiency anemia, chronic liver disease, alpha thalassemia.

19

What is pica?

Eating non food items including ice, paper, dirt, hair.

20

Are target cells seen in mild or severe iron deficiency anemia?

Severe, they are also seen in alpha thalassemia, chronic liver disease and asplenia.

21

Iron deficiency anemia will have a serum iron lower than what value?

30

22

Would a B12 deficiency anemia most likely be microcytic, normocytic or macrocytic?

Macrocytic

23

You should be thinking alpha thalassemia if the question stem includes which four geographic areas?

Southeast Asia, China, Middle East, Africa

24

A patient of mediterranean descent is a clue for which type of anemia?

Beta thalassemia

25

In a folic acid deficiency anemia the folic acid level is typically below what level?

<150

26

What hematological disorder should you think of if the questions talks about the patient eating ice or dirt?

Iron deficiency anemia

27

Inability to absorb vitamin B12 due to lack of intrinsic factor is what disease?

Pernicious anemia

28

Stocking glove paresthesias should make you think of what two diagnoses?

B12 deficiency neuropathy and diabetic neuropathy.

29

Will the RBC's be large, small or normal size in a B12 deficient anemia?

Macrocytes

30

Will the retic count be elevated, decreased or normal in a B12 deficient anemia?

Retic count will be low. Low building blocks means low production.

31

What is Schilling's test used for?

Test for the cause of a B12 deficiency.

32

Strict vegans are at risk for what type of anemia?

B12 deficiency anemia

33

Is sickle cell microcytic, macrocytic or normocytic?

Microcytic

34

Will a hemolytic anemia generally have an elevated or or decreased retic count?

Elevated

35

List four disease states in which you may find basophilic stippling.

Lead poisoning, Beta or alpha thalassemia, sideroblastic anemia, arsenic poisoning.

36

If a question presents a pregnant woman with anemia what is the most likely diagnosis?

Iron deficiency

37

The term Philadelphia chromosome you should make you think of what diagnosis?

Chronic myeloid leukemia