Histow Flashcards

(162 cards)

1
Q

% composition of enamel? What is the main mineral component?

A

96% inorganic
Calcium phosphate aka Hydroxyapatite arranged in prisms
1% amelogenins (main protein) and enamelins contained in enamel tuft
3% water

*Dentin: 70% inorg
*cementum: 55% inorg (calcium salts)

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2
Q

Enamel prisms are arranged…

A

Approximately PERPENDICULAR to the dentin at the dentinoenamel junction following a wavy course towards enamel surface

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3
Q

Gnarled enamel vs straight enamel

A

Gnarled enamel - prisms are twisted in a random manner, located over cusps and ridges of premolars and molars, rarely fractures

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4
Q

Shallow, transverse, wavelike grooves visible under reflected light parallel to the CEJ, surface manifestation of the lines of Retzius

A

Perikymata / imbrication line of Pickerill
- encircles the surface of enamel on anatomic crown

Some sources: perikymata - cervical ridges
Imbrication lines - grooves between

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5
Q

Brown lines seen in ground sections at the enamel

A

Incremental striae (lines of Retzius)
-indicate variations in deposition of organic matter in enamel which later calcifies

Hypomineralized area

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6
Q

Line where enamel is being deposited at birth

A

Neonatal line
- represents accentuated lines of Retzius
- reflects metabolif changes at birth
-present in dentin

Enamel Internal to it: formed before birth and has fewer defects
Enamel External to it: formed after birth

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7
Q

Alternating light and dark bands seen under oblique reflected light in longitudinal ground sections

A

Hunter-Schreger bands - DEJ to external surface of enamel / inner 2/3 of enamel (due to periodic changes in the enamel prism direction)

LIGHT ZONE: PARAZONE
DARK ZONE: DIAZONE

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8
Q

Area of poorly calcified enamel that extend from outer surface into the tissue for variable distances

A

Enamel lamellae - sometimes completely through underlying dentin

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9
Q

Extension of adjacent odontoblastic processes that continue into enamel (left behind kasi)

A

Enamel spindles - various terminations (pointed, sharp, rounded)

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10
Q

Areas of hypocalcification in prisms and interprismatic material (calcification imperfections in enamel prisms) that starts at DEJ and penetrates into enamel

A

Enamel tufts - start at DEJ and penetrate into enamel about 1/3 of its thickness

Enamelin: organic material in enamel tufts

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11
Q

Some patients experience pain on tooth may be due to:
A. Enamel Tufts
B. Enamel lamellae
C. Enamel spindles
D. Striae of Retzius

A

C

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12
Q

Cause of sclerosis in dentinal tubules

A

Increase formation of peritubular dentin = decrease permeability

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13
Q

Optical phenomenon due to cyclic activity of the odontoblasts during dentin formation

A

Incremental lines of von Ebner (perpendicular to the dentinal tubules)

Sa DENTIN TO!!

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14
Q

Completion of radicular dentin formation

A

(closure of apex)
Primary: 18months after eruption
Permanent: 2-3yrs after eruption

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15
Q

Tomes fiber vs tomes process

A

Odontoblastic process: tomes fiber
Ameloblast extension: tomes process (responsible for enamel secretion)

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16
Q

Main bulk of dentin?

A

Intertubular dentin

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17
Q

Immediate wall material which is the peritubular dentin was previously called?

A

Sheath of Neumann

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18
Q

Type of dentin that lines the pulp?

A

Secondary dentin -can sometimes obliterate the pulp

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19
Q

Type of dentin that develops at localized sites stimulated by local irritation

A

Tertiary or reparative or irregular dentin

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20
Q

Type of dentin resulting from stimuli that causes calcification of the odontoblastic process

A

Sclerotic or transparent dentin - hypercalcification = harder and denser dentin

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21
Q

Seen where tome’s process has disintegrated

A

Dead tracts in dentin - black in transmitted light, white in reflected light

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22
Q

Location of cellular and acellular cementum

A

Acellular deposited slowly from CEJ to 2/3 of root

Cellular rapidly forms and predominantly in apical 3rd and furcations

Two types mingle in the apical 3rd of the root

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23
Q

Most common type of CEJ

A

Acellular cementum overlaps the cervical enamel (60%)
Cementum and enamel meet at a sharpt point (30%)
No direct connection (10%)

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24
Q

Involved in dentin formation that originates in the pulp

First sign of mantle dentin formation

A

Von Korff’s fibers - type 3 collagen fibers (reticular) + fibronectin

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25
Calcospherites failed to fuse completely will result to?
Areas of dentin matrix with tubules that are incompletely calcified (interglobular dentin frequently near DEJ)
26
Principal fibers that can prevent rotation of the tooth and preclude occlusal displacement
Alveloar crest fibers - cervical cementum to alveolar crest **Horizontal fibers can also check rotation of the tooth (cervical cementum horizontally to alveolar bone)
27
Principal fiber that prevents tooth from being forced into the socket
Oblique fibers - cementum occlusally to alveolar bone (obliquely), largest group
28
Fibers that prevent rotation of tooth by radiating out like a fan from the apical region of root
Apical fibers
29
Fibers that maintain the mesiodistal relations
Transseptal fibers
30
Alveolar process two regions: internal cancellous layer and lamina dura. Other name for lamina dura?
Cribriform plate - it contains many apertures for vessels coursing between the marrow cavities and the PDL
31
Type of bone that lines the socket after teeth have been subjected to stress
Bundle bone
32
periods of prenatal development
proliferative (0-2 weeks IU) least vulnerable embryonic (2-8 weeks IU) most vulnerable fetal (8 weeks-9 months)
33
16 cell zygote
morula *blastocysts is when there is a fluid filled center (yolk sac)*
34
lines the primary yolk sac and aids implantation (becomes placenta)
trophoblast cells -digests endometrial cells *embryoblast will form bilaminar germ disk or embryonic disk (embryo proper)*
35
two-layered disk
bilaminar germ disk or embryonic disk becomes: ectodermal layer: lines amniotic cavity endodermal: lines yolk sac
36
before placenta forms, what provides nutrition of embryo? ... through??
yolk sac through vitelline arteries
37
week when bilaminar becomes trilaminar disk? what is it called?
period of gastrulation 3rd week of gestation
38
gastrulation and neurulation events
3rd week ectodermal layer thickens (neural plate) --> neural folds --> neural groove --> meets at the middle --> neural tube (brain and spinal cord) migration of *neural crest cells/ ectomesenchyme* (from ectoderm) becomes face and teeth **EXCEPT ENAMEL**; gives rise to neural, endocrine, pigment cells, skeleton, **CT of head and neck**
39
when: heart begins to beat?
4th week
40
derivatives of ectoderm, mesoderm, endoderm
**ectoderm** nervous system sensory epithelium of eye, ear, nose mammary and cutaneous glands epithelium of the sinuses, oral and nasal cavities, intraoral glands tooth enamel CT of head and neck **mesoderm** muscles CT derivatives (bone, cartilage, blood, PDL, cementum, pulp etc) **endoderm** GI tracct lungs liver, gallbladder, pancreas urinary bladder
41
when is the neural tube formed/fused?
18 days - 20 days
42
when: facial development
3rd to 7th week IU
43
four major tissue masses for facial development
frontonasal process LEFT AND RIGHT maxillary processes (PA1) mandibular process (PA1)
44
3rd Week IU
rapidly developing brain + heart = **embryo folds** *stomodeum - primitive mouth; bounded by frontal prominence and PA1 *presence of buccopharyngeal membrane (ectoderm and endoderm) end of 3rd week: first PA has divided into right and left Maxillary process and mandibular process
45
separates the primitive mouth from the foregut
buccopharyngeal membrane - ecto and endoderm
46
4th week IU
buccopharyngeal membrane **disintegrates** **nasal pits** on the *frontonasal process* --> median nasal process, left and right lateral process heart begins to beat tongue begins to develop
47
5th week IU
fusion of medial nasal process --> philtrum, middle of upper lip, **globular process* --> primary palate/premaxilla lateral nasal process forms the ala of nose eyes become prominent at the side Md arch loses midline constriction
48
6th week IU
lateral growth of brain broadening of face upper lip forms (MxP + MNP) 6 auricular hillocks (hillocks of His) - from BA1 and BA2 (pharyngeal grooves?) --> external ear
49
7th week IU
eyes approach front of face development of the secondary palate --> completed by 3rd month maxi process --> two palatine shelves develop --> secondary palate palatine shelves + nasal septum --> separation of oral and nasal cavities **PALATE DEVELOPMENT**
50
what forms the upper lip??
Maxillary process + median nasal process *failure of fusion = cleft lip
51
when and how: palate development
starts 7 weeks IU palatal closure: approx 12 weeks from globular process of MNP --> premaxilla/primary palate from palatine shelves of L&R maxi process --> secondary palate *FUSION OF PRIMARY is from posterior to anterior *FUSION OF SECONDARY is from anterior to posterior **may contact sa gitna kasii tas dun magstart magfuse
52
when and how: development of tongue
4 weeks IU anterior 2/3 -right and left lateral swellings + tuberculum impar of (BA1) posterior 1/3 - posterior to old buccopharyngeal membrane -Copula (BA2) + hyprobranchial eminence (BA3 and BA4) --> eminence grows OVER copula (matatakpan) -epiglottal swelling (BA4)
53
marks the development of epiglottis
posterior part of the 4th BA (epiglottal swelling
54
former location of thyroid gland
foramen cecum --> bababa thyroid with thyroglossal duct (parang string then mawawala)
55
facial and palatal clefts: critical period?
6th and 7th week IU
56
oblique facial cleft is the failure of fusion of?
lateral nasal process and maxillary process
57
bilateral cleft lip is the failure of fusion of?
median nasal process and left and right maxillary process
58
median cleft lip is the failure of fusion of?
left and right median nasal process at midline *magkalayo ang median nasal process before kasi
59
lateral facial cleft is the failure of fusion of?
maxillary process and mandibular process
60
only BA that extend to the midline??
BA1 and BA2
61
How was the smooth surface of neck formed? when?
fusion of BA2 and BA5 to eliminate features of 2, 3, 4 BA 5th week!
62
BA1 structures?? (Mandibular arch)
**Maxillary** artery Trigeminal nerve MOMs tensor tympani and tensor veli palatini mylohyoid **anterior** belly of digastric malleus, incus, sphenomandibular, Meckel's external ear, middle ear, eustachean tube
63
BA2 structures?? (hyoid)
hyoid artery, stapedial artery facial nerve MOF stapedius, stylohyoid, POSTERIOR digastric **stylohyoid ligament** LESSER horn of hyoid supratonsillar fossa
64
BA3 structures
internal carotid artery glossopharyngeal nerve **stylopharyngeus** GREATER horn of the hyoid INFERIOR parathyroid gland thymus
65
BA4 structures
right subclavian artery aorta Vagus nerve levator veli palatini palatoglossus pharyngeal constrictors cricothyroid SUPERIOR parathyroid gland
66
from what B.A is the parafollicular cells from?
parafollicular cells of thyroid gland (calcitonin) is from BA5
67
BA: hyoid??
both BA2 (lesser) and BA3 (greater horn)
68
horseshoe shape that will correspond in position to the future dental arches (week??)
Primary epithelial band (6th week IU) -invagination of the thickened band of oral epithelium into the ectomesenchyme (NCC)
69
primary epithelial band will divide into?? contribute to?? (week??)
7th week 1. dental lamina - development of teeth 2. vestibular lamina - vestibule of mouth
70
local thickening that develop within the dental lamina corresponding to the positions of the 20 primary teeth?
dental placodes - will proceed to the bud, cap, bell stage *successional lamina - LINGUAL extensionn that will give rise to the succedaneous teeth
71
three parts of tooth germ in the cap stage
enamel organ (from dental lamina) - enamel dental papilla (from ectomesenchyme) - pulp-dentin complex dental follicle (from ectomesenchyme) - cementum, pdl, alveolar process
72
3 layers of enamel organ
outer enamel epithelium inner enamel epithelium stellate reticulum - between IEE OEE *cap stage
73
bell stage histodifferentation
IEE --> becomes pre-ameloblast --> urges adjacent cell to become pre-odontoblast --> mature odontoblast --> lays down uncalcified pre-dentin --> calcification of dentin induces --> maturation of ameloblast --> enamel deposition
74
site of CEJ
Cervical loop - formed when IEE and OEE meets; gives rise to Hertwig's and epithelial diaphragm seen in Bell stage
75
remnant of dental lamina entrapped within gingiva; important in pathology
cell rests of Serres
76
signals site of future cusp tips
enamel knot
77
First dentin formed is found at?
Incisal or cusp area *Towards cervical loop*
78
new layer of collagenous dentinal matrix laid down not yet mineralized
Predentin
79
How many microns of dentin is deposited and mineralized?
During crown development and eruption: 4microns deposited in a 24 hr period 2microns mineralized in a 12 hr period Period of function: Less that 1 micron deposited per day
80
First and outermost layer of dentin
Mantle dentin mineralized by globular mineralization aka calcospheric mineralization
81
Succeeding layers formed after mantle dentin
Circumpulpal dentin (linear mineralization)
82
Picket fence or saw tooth appearance between enamel and ameloblast
Tome's process --> rod and interrod structure of enamel **Ameloblastoma
83
Very first and very last layer of enamel to be laid down
Prismless enamel
84
Responsible for Maturation of enamel
Ruffle ended ameloblast: adds calcium Smooth ended ameloblast: removes organic part
85
Globular mineralization of mantle dentin
Von korff's -> odontoblast secrete matrix vesicles which contain HAP crystals --> increase size of HAP --> HAP breaks out from vesicle --> touch each other pero may gaps (interglobular dentin)
86
Contributes to the reduced enamel epithelium
IEE OEE *Stellate reticulum *S. Intermedium
87
How was hertwig's root sheath formed
Aka epithelial root sheath *Cells in the cervical loop (IEE + OEE) proliferate
88
Acellular cementum that covers the ends of dentinal tubules and seals root surface
Intermediate cementum
89
Remnants of HERS in PDL
Epitheloal cell rests of Malassez
90
Uncalcified cementum? Secreted by?
**Cementoid** secreted by cementoblast that differentiated due to tooth follicle being in contact with the exposed root surface
91
Area where root sheath bends at 45-degree angle
Epithelial diaphragm
92
Responsible for the formation of multi-rooted teeth
Epithelial diaphragm -encircles apical opening of the dental pulp during root development
93
Development of root
Cervical loop - HERS - odontoblast differentiation (inner) to form dentin - HERS deposit intermediate cementum - root sheath cells disperse away (Malassez) - mesenchymal cells differentiate to cementoblast - cementoid - cementum
94
Eruptive movements phases
1. Pre eruptive - movement made by primary and permanent tooth germs w/in tissues of jaw 2. Eruptive - within crypt to functional position 3. Functional eruptive /post eruptive
95
Pre-eruptive movement of primary and permanent teeth (direction/location)
Primary - facial and occlusal or with growth of face Developing permanent anterior - lingually near apical 3rd of primary Developing permanent premolars - furcation of primary molars Developing permanent molars -upper molars: develop in Mx tuberosities **occlusal surfaces slanting distally** -lower molars: develop in the base of mandibular rami with**surface slanting mesially**
96
When does the eruptive phase begin? First clinical sign?
Begins with the initiation of root formation and ends when the teeth reach occlusal contact Emergence is the first clinical sign
97
Contributes to the junctional epithelium
REE + oral epithelium
98
Believed to guide teeth towards complete tooth eruption
Gubernacular cord aka gubernacular dentis contained in gubernacular canals *present on succedaneous teeth*
99
Delicate membrane that covers the entire crown of newly eruptive teeth (2 names and from what structure??)
Primary enamel cuticle aka Nasmyth's membrane from reduced enamel epithelium. Removed by mastication
100
Causes for functional eruptive / posteruptive phase
Accommodation of growth Compensation for occlusal wear Accommodation for interproximal wear
101
Factors that can cause mesial drift (functional eruptive)
Anterior component of occlusal force Contraction of transseptal ligament Soft tissue pressures
102
Contributes to the ruffled-border appearance that suggests resorption of primary tooth
Odontoclast Causes of exfoliation: odontoclast and pressure from erupting successional teeth **Submerged teeth** successional tooth does not exist
103
Boundrary between rod and interrod enamel is delimited by a narrow space containing **organic** material called?
Rod sheath
104
Predominant form of human enamel (cross section)
Pattern III: Keyhole pattern Pattern I: Circular Pattern II: aligned in parallel rows
105
Represents 24-hour cycle of incremental growth of enamel
Cross striations (short term apposition)
106
Represents incremental growth pattern of enamel over a week or 5-10 days (longitudinal and cross section???)
Enamel striae aka incremental lines of Retzius -Longer apposition Longitudinal: oblique lines from DEJ to surface Cross-sectional: concentric lines
107
initiation bud stage cap stage bell stage appositional stage happens in what week?
initiation = 6th week bud = 8th week cap = 9th week bell = 11th week appositional = 14th week
108
defects that can occur due to abnormalities during the initiation stage?
anodontia or supernumerary
109
defects that can occur due to abnormalities during the cap stage?
dens in dente, gemination, fusion, tubercles
110
defects that can occur due to abnormalities during the appositional stage?
enamel dysplasia, concrescence, enamel pearls
111
last layer of enamel secreted by ameloblast
Nasmyth membrane / primary enamel cuticle
112
membrane between enamel organ and dental papilla, makes the DEJ
membrane performativa -gives rise to shape of crown
113
defects that can occur due to abnormalities during the bell stage?
dentinogenesis and amelogenesis imperfecta, micro/macrodontia
114
mineralization stage takes ___ to complete
2 years; it starts at DEJ = first enamel and dentin is formed here
115
composition of dentin
70% inorganic calcium hydroxyapatite crystals 20% organic (mostly type 1 collagen) 10% water
116
directly underlies mantle dentin and comprises the bulk of the tooth's primary dentin
circumpulpal dentin - contains smaller in diameter and more randomly oriented collagen fibers *more mineralized than mantle dentin.
117
reactionary vs reparative dentin
both are tertiary type of dentin reactionary - from preexisting odontoblast and due to mild injury. tubular and continuous with primary and secondary dentin reparative / **osteodentin** - newly differentiated odontoblast, more severe pulpal incure, atubular, deposited immediatedly adjacent to it
118
path of dentinal tubules seen in ground sections
crown: S shaped root: straight *dentinal tubules are larger near the pulp, more surface area of dentin, and there's increased number of tubules
119
primary content of the dentinal tubule
Tome's process *if it dies or distintegrates, = empty dentinal tubules = dead tracts
120
band of newly formed unmineralized matrix of dentin at the pulpal border of dentin adjacent to odontoblast
predentin
121
dentin matrix that immediately surrounds the dentinal tubule (hyper or hypomineralized?)
peritubular dentin / intratubular dentin hypermineralized collar --> if completely fills the tubules --> **sclerotic dentin / transparent dentin** / calcified dentin
122
type of dentin located between and around the dentinal tubules
intertubular dentin (it is less calcified than peritubular dentin)
123
zone between the peritubular and intertubular dentin (hyper or hypomineralized?
Sheath of Neuman
124
represents the daily deposition of 4 micros of dentin. what is the counterpart in enamel and cementum?
incremental lines of von ebner enamel - IL of retzius cementum - IL of Salter
125
results from the coincidence of secondary curvatures between dentinal tubules
contour lines of Owen
126
hypomineralized region of dentin only present in the root; looping of terminal tubules
Granular layer of tomes
127
four distinct zones of the pulp
1. odontoblastic zone - processes extend into dentin; zone is more pronounced in the coronal pulp; in the rad pulp and furcation areas, odontoblasts are more cuboidal rather than columnar 2. cell-free zone of Weil - contains capillaries, unmyelinated fibers; **subodontoblastic plexus of Raschkow** - present in coronal pulp 3. cell-rich zone - contains lymphocytes, dendritic, macrophages 4. pulp proper - blood vessels of the pulp, nerve endings
128
most abuntant cells found in the dental pulp (and all cells found in the pulp)
**fibroblast** odontoblast undifferentiated ectomesenchymal cells macrophages (histiocytes or wandering cells) and dendritic cells
129
Pain theories and the pulp-dentin complex
1. direct innervation theory - nerves extend to DEJ 2. transduction theory - odontoblastic process is the pain receptor that conducts pain to nerve endings presend in the pulp 3. hydrodynamic theory / Brannstrom - pain is caused by stimuli that produce fluid movement and disturbs the odontoblastic processes within the dentinal tubules
130
pulp changes with age
DECREASE in pulp size, cellularity, capability of repair INCREASE in fibrosis, pulp stones/denticles (pulp chamber), diffuse calcifications (root canal) true denticles - with dentinal tubules false denticles - concentric layers of calcified tissue
131
marker for areas where resorption may have occurred but cementum repair takes place to reverse effects
reversal lines
132
first cementum to be deposited on the root
intermediate cementum / Hyaline layer of Hopewell Smith formed by IEE of HERS located between tome's granular layer and primary cementum
133
types of cementum
acellular cementum / primary cementum - initial layer of cementum deposited on the intermediate cementum - cervical 3rd cellular/ secondary cementum - apical 3rd and interradicular regions of premolars and molars - associated with **repair**!!
134
processes of the cementocytes that extend through narrow channels
canaliculi
135
extrinsic fibers embedded into the cementum which run **perpendicular** to root surface
Sharpey's fibers intrinsic fiber - runs parallel to root surface produced by cementoblasts
136
composition of alveolar bone
60% inorganic (hydroxyapatite crystals 25% organic (type 1 collagen) 5% water
137
Alveolar process type of bone absent in the anterior region
trabecular or spongy bone *red marrow - mostly in mandi *yellow marrow - mostly in the maxi
138
bone that lines the socket
bundle bone or cribriform plate -XR: lamina dura
139
width of the alveolar crest
determined by shape of adjacent teeth narrow crest: between teeth with relatively flat surface widened crest - teeth with convex surface or teeth with diastema
140
principal collagen fibers embedded in the alveolar proper (bundle bone)
sharpey's fibers
141
composition of PDL
mostly collagen fibers mostly type 1; some **oxytalan** fibers = regulation of vascular flow
142
gingival fiber group that resists gingival displacement
circular / circumferential fibers - extends around the tooth at the level of the CEJ
143
gingival fiber group that causes the relapse of rotated teeth
transseptal fibers - from cementum of one tooth to the adjacent tooth
144
peridontal fiber group that resists vertical
interradicular group (furcation to alveolar bone proper) apical group to resist extrusion / vertical -- alveolar crest and oblique group - resist vertical and intrusive - Horizontal group to resist horizontal and tipping forces
145
lamina propria layers
papillary layer - collagen are thin and loosely arranged with many capillary loops reticular layer - deeper, thicker layer; collagen fibers are arranged in thick bundles
146
orthokeratinized vs parakeratinized
ortho - no nucleus in s. CORNEUM para - pyknotic nuclei in s CORNEUM
147
Oral mucosa: areas covered with lining mucosa, masticatory mucosa, and specialized mucosa
lining mucosa: FOM, buccal mucosa, **alveolar mucosa**, lips, soft palate, ventral surface of tongue (epithelial ridges are fewer) masticatory: hard palate, alveolar ridges, gingiva specialized: dorsum of tongue
148
only kind of specialized mucosa that is lined with keratinized epithelium
filiform papillae - tough, abrasive surface
149
location of taste buds
trench of circumvallate lateral walls of foliate fungiform mucosa of soft palate epiglottis
150
types of cells located in the taste bud
supporting cells / sustentacular cells - periphery of tase buds neuroepithelial cells / gustatory cells / taset cells - elongated microvilli that project into the tase pore or shortened villi into the base of the pore; assoc with nerves
151
contractile cells that surronds the ducs and acini. it contains myofilaments similar to smooth muscle fibers
myoepithelial cells aka basket cells
152
differentiate serous cells, mucous cells, serous demilunes (other name)
serous - secretes zymogen granules - amylase - watery consistency mucous - secretes muciin - viscous - lubricant serous demilunes /**Demilunes of Gianuzzi** - terminal mucous cells with a cap of serous demilunes will secrete a mixed product
153
INTRAlobular duct system
intercalated ducts - receives secretions from acini, simple cuboidal, saliva is isotonic, contributes lactoferrin and lysozyme striated - main intralobular ductal component, simple columnar, receives secretions from intercalated, hypotonic (sodium reabsorption + K excretion) interlobular excretory ducts - pseudostratified columnar cells (excretory ducts) acini is simple cuboidal
154
minor salivary glands in the peritonsillar region and type of secretion
weber's gland - mucous
155
minor salivary glands in the retromolar area
carmalt's gland
156
contents of dentinal tubules
odontoblastic process, periodontoblastic space (contains dentinal fluid), intratubular nerve (from plexus of Rashkow)
157
nerve supply of pulp
rashkow's plexus, sympathetic and afferent
158
nerve supply, vascular, lymphatics of PDL
maxillary artery trigeminal nerve submandibular lymph nodes
159
collagen type in the basement membrane
type IV and laminin
160
areas in the oral mucosa where submucosa is not present
attached gingiva, hard palate, tongue
161
The amount of collagen in a tissue can be determined by its?
Hydroxyglycine Collagen contains AA: glycine, proline, hydroxylysine, hydroxyproline
162
Smallest neuron in the brain
Granule cells