Hormone Contraception - Linger

Question 1

human menopause gonadotropin

Answer 1

menotropin

Question 2

chorionogonadotrope alpha

Answer 2

RhCG

Question 3

pulsatile gonadotrope

Answer 3

stimulatory

Question 4

conjugated estrogen

Answer 4

premarin

natural

less potent

Question 5

synthetic estrogens

Answer 5

estradiol valerate
ethinyl estradiol
mestranol

Question 6

norethindrone

Answer 6

progestin

Question 7

etonogestrel

Answer 7

active progestin - desogestrel

Question 8

desogestrel

Answer 8

inactive prodrug - progestin

Question 9

drospinenone

Answer 9

progestin

Question 10

porgestimate

Answer 10

progestin

Question 11

norgestrel

Answer 11

progestin

L and levo also - L isomer is active

Question 12

mifepristone

Answer 12

progesterone receptor antagonist

induces leutolysis

Question 13

anastrazole

Answer 13

aromatase inhibitors

Question 14

exemestane

Answer 14

aromatase inhibitors

Question 15

letrozole

Answer 15

aromatase inhibitors

Question 16

clomiphene

Answer 16

selective estrogen receptor downregulator

Question 17

fulvestrant

Answer 17

selective receptor receptor downregulator

Question 18

tamoxifen

Answer 18

selective estrogen receptor modulator

Question 19

ER receptor positive breast ca resistant to tamoxifen

Answer 19

fulvestrant

Question 20

women with fibroids

Answer 20

give no estrogen

Question 21

hormone contraception

Answer 21

estrogen/progestin combo

progestin only

Question 22

estrogen receptor

Answer 22

alpha and beta isoforms

bind ligand and HSP disocciation
leads to dimerization of receptor

Question 23

CI of estrogen

Answer 23

undiagnosed genital bleeding

heavy smoker

Question 24

protective against endometrial cancer

Answer 24

estrogen/progestin combo

Question 25

OTC ovulation kit

Answer 25

measures LH levels

Question 26

hCG

Answer 26

from placenta | -acts on LH receptors

Question 27

estrogen in contraceptive

Answer 27

ethinyl estradiol

Question 28

injectable contraceptive

Answer 28

medroxyprogesterone acetate

Question 29

nuvaring

Answer 29

ethinyl estradiol etonegestrol rapid return to fertility*

Question 30

transdermal contraception

Answer 30

ethinyl estradiol | norelgestromin

Question 31

IUD

Answer 31

levonorgestrel - mirena rapid return to fertility

Question 32

implantable contraceptive

Answer 32

etonogestrel rapid return to fertility

Question 33

plan B

Answer 33

levonorgestrel

Question 34

ella

Answer 34

ulipristal acetate prescription emergency contraception

Question 35

estrogen in HRT

Answer 35

premarin - natural conjugated estrogen less potent

Question 36

breakthrough bleeding

Answer 36

progestin only contraceptives

Question 37

medroxyprogesterone acetate hormonal

Answer 37

androgenic | antiestrogenic

Question 38

desogestrel hormonal

Answer 38

none

Question 39

norethindrone hormonal

Answer 39

androgenic

Question 40

L-norgestrel hormonal

Answer 40

androgenic

Question 41

progesterone receptor

Answer 41

A and B isoforms

Question 42

progestin half life

Answer 42

5 minutes

Question 43

HRT with estrogen and progestin

Answer 43

increased breast ca | decreased endometrial ca

Question 44

progestin only contraceptive

Answer 44

don't block as well - but have other mechanisms of action - thick mucus - endometrial alterations

Question 45

endometrial hyperplasia

Answer 45

prevented with progestin

Question 46

lowest failure rate

Answer 46

implantable etonogestrel

Question 47

failure of oral contraceptive

Answer 47

8%

Question 48

termination of pregnancy

Answer 48

mifepristone and misoprostol (PGE2)

Question 49

clomiphene

Answer 49

partial agonist at estrogen receptors

Question 50

prescription morning after

Answer 50

ullipristal acetate

Question 51

agonist at lipid and bone, antagonist on endometrium and breast

Answer 51

raloxifene

Question 52

tamoxifen MOA

Answer 52

competitive partial agonist inhibitor of estradiol at estrogen receptor

Question 53

hirsutism

Answer 53

norethindrone | levonorgestrel

Question 54

primary hypogonadism

Answer 54

estrogen therapy | after 1st bleeding - add progestin

Question 55

CI for estrogen only contraceptive

Answer 55

smoker >35yo | no HTN, CAD, diabetes

Question 56

SERM

Answer 56

tamoxifen and toremifene adverse - hot flashes

Question 57

oral estrogen vs. transdermal

Answer 57

more effect on circulating proteins produced by liver transdermal - decreased change serum lipids

Question 58

estrogen and lipids

Answer 58

increased HDL and TGs | decreased LDL and cholesterol