Hormone Contraception - Linger Flashcards Preview

REPRO II Exam 1 > Hormone Contraception - Linger > Flashcards

Flashcards in Hormone Contraception - Linger Deck (58):
1

human menopause gonadotropin

menotropin

2

chorionogonadotrope alpha

RhCG

3

pulsatile gonadotrope

stimulatory

4

conjugated estrogen

premarin

natural

less potent

5

synthetic estrogens

estradiol valerate
ethinyl estradiol
mestranol

6

norethindrone

progestin

7

etonogestrel

active progestin - desogestrel

8

desogestrel

inactive prodrug - progestin

9

drospinenone

progestin

10

porgestimate

progestin

11

norgestrel

progestin

L and levo also - L isomer is active

12

mifepristone

progesterone receptor antagonist

induces leutolysis

13

anastrazole

aromatase inhibitors

14

exemestane

aromatase inhibitors

15

letrozole

aromatase inhibitors

16

clomiphene

selective estrogen receptor downregulator

17

fulvestrant

selective receptor receptor downregulator

18

tamoxifen

selective estrogen receptor modulator

19

ER receptor positive breast ca resistant to tamoxifen

fulvestrant

20

women with fibroids

give no estrogen

21

hormone contraception

estrogen/progestin combo

progestin only

22

estrogen receptor

alpha and beta isoforms

bind ligand and HSP disocciation
leads to dimerization of receptor

23

CI of estrogen

undiagnosed genital bleeding
heavy smoker

24

protective against endometrial cancer

estrogen/progestin combo

25

OTC ovulation kit

measures LH levels

26

hCG

from placenta
-acts on LH receptors

27

estrogen in contraceptive

ethinyl estradiol

28

injectable contraceptive

medroxyprogesterone acetate

29

nuvaring

ethinyl estradiol
etonegestrol

rapid return to fertility*

30

transdermal contraception

ethinyl estradiol
norelgestromin

31

IUD

levonorgestrel - mirena

rapid return to fertility

32

implantable contraceptive

etonogestrel

rapid return to fertility

33

plan B

levonorgestrel

34

ella

ulipristal acetate

prescription emergency contraception

35

estrogen in HRT

premarin - natural conjugated estrogen

less potent

36

breakthrough bleeding

progestin only contraceptives

37

medroxyprogesterone acetate hormonal

androgenic
antiestrogenic

38

desogestrel hormonal

none

39

norethindrone hormonal

androgenic

40

L-norgestrel hormonal

androgenic

41

progesterone receptor

A and B isoforms

42

progestin half life

5 minutes

43

HRT with estrogen and progestin

increased breast ca
decreased endometrial ca

44

progestin only contraceptive

don't block as well - but have other mechanisms of action - thick mucus - endometrial alterations

45

endometrial hyperplasia

prevented with progestin

46

lowest failure rate

implantable

etonogestrel

47

failure of oral contraceptive

8%

48

termination of pregnancy

mifepristone and misoprostol (PGE2)

49

clomiphene

partial agonist at estrogen receptors

50

prescription morning after

ullipristal acetate

51

agonist at lipid and bone, antagonist on endometrium and breast

raloxifene

52

tamoxifen MOA

competitive partial agonist inhibitor of estradiol at estrogen receptor

53

hirsutism

norethindrone
levonorgestrel

54

primary hypogonadism

estrogen therapy
after 1st bleeding - add progestin

55

CI for estrogen only contraceptive

smoker >35yo
no HTN, CAD, diabetes

56

SERM

tamoxifen and toremifene

adverse - hot flashes

57

oral estrogen vs. transdermal

more effect on circulating proteins produced by liver

transdermal - decreased change serum lipids

58

estrogen and lipids

increased HDL and TGs
decreased LDL and cholesterol