Ilan Tumor Metabolism 2

Question 1

What is a metabolic reprogramming that the cancer cell does

Answer 1

Change in the cell metabolism in order to survive better in conditions of lack of oxygen and lack of glucose

Question 2

When cancer cell leave the blood vessels what does he look first glucose or oxygen

Answer 2

Oxygen

Question 3

How does a cancerous cell change its environment

Answer 3

Grows new blood vessels in the endothelial cells

Question 4

What are the roles of the glycolysis in cancerous cells

Answer 4

Both ATP production and biosynthesis

Question 5

What is veburg effect

Answer 5

Increased glycolysis in tumors

Question 6

Which functions are part of the Warburg effect

Answer 6

Rapid ATP synthesis at the tumor microenvironment biosynthesis and cell signaling

Question 7

Which are two main signals for cancer developments

Answer 7

 Tumor promoting inflamation and unbalanced and tendency for gene mutations

Question 8

What is the weber effect

Answer 8

Increasing the glucose phosphte pathway by activation of glucose six phosphate dehydrogenase

Question 9

What is the ROS theory

Answer 9

High rate of ROS production due to Changes in that respiratory of the cells

Question 10

How the hif1 alpha gene helps tumors to prolifirate

Answer 10

Promote expression of transporters of glucose and enzymes and promotes to switch from pyruvate to lactate metabolism

Question 11

How the MYc gene influence the cancer procecess

Answer 11

Does serious function that helps the tumor to survive

Prevents hypoxia