Dani Brain 2 Flashcards

1
Q

How much of our brain is fat

A

60%

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2
Q

How myelin allowed development of brain in vertebrates

A

Conducting nerves faster and decrease in size of nerves

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3
Q

Which glial cell produces myelin sheet

A

Oligodendrocyte

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4
Q

What does the myelin consist off

A

80% of fat and 20% protein

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5
Q

Which types of protein are Present in the myalin

A

Proteolipid protein
Myelin basic protein
Myelin oligodendrocyte glycoprotein

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6
Q

Does young children has Myelin

A

No

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7
Q

Which type of cells generates myalin

A

Oligodendrocytes and Schwann cells

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8
Q

How many axons does the Schwann cell can cover

A

1

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9
Q

How many neurons each oligodendrocyte cover

A

Up to 50 exons

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10
Q

When the myelination process is complete, is there a possibility of production new myelin?

A

Yes. Through learning new tasks

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11
Q

In which area of the brain, the gray matter is located

A

In the outer part of the brain

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12
Q

Which cells are considered part of the gray matter of the brain

A

Axons without myelin
Glial cells
capillary blood vessel
neutrophils

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13
Q

Which type of cells the white matter contained

A

Oligodendrocytes and strocytes

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14
Q

Which type of matter in the brain consist Myelinated cells

A

White matter

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15
Q

What does the oligodendrocyte consume as an energy source

A

Glucose and lactate

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16
Q

Which product can the oligodendrocyte send

17
Q

To witch sub groups we split the myelin related diseases

A

Loss of myelin and defects in the development of them myelin

18
Q

Which types of diseases caused due to the Myelination

A

Multiple sclerosis

Gillian beret syndrome

19
Q

What ae the Dysmyelination dieseas

A

Pelizaeus merzbacher Disease
Cannavan disease
Schizophrenia

20
Q

Which nervous system multiple sclerosis is related to

A

Central nervous system (CNS)

21
Q

Which part of the brain cell is damaged during MS

22
Q

Which gender suffers more from multiple sclerosis

23
Q

In which race MS is more common

A

Caucasians

24
Q

Which groups of fatty acid are present in the brain

A

Sphingolipids
Phospholipid
Cholesterol

25
What does the fatty acid function for
Signaling molecules sources of energy | synaptogenesis neurogenesis impulse condition and other
26
What is the main usage of lipids for the brain
Utilize acylated lipids to generate phospholipids for cell membrane
27
How leptin affect energy expenditure in the brain
Increase it
28
How leptin increases the energy expenditure in the brain
Buy acting on hypothalamic centers that increases fatty acids flow
29
How much of the body cholesterol is located in the brain
I'm about to 25%
30
Where does the brain cholesterol is produced
In the brain because it cannot cross the brain blood barrier
31
Which type of cholesterol can cross the blood brain barrier
Very dense HDL
32
Which regulatory element binding protein regulates the production cholesterol
SREBP2
33
Which neural cells is the main producer of cholesterol in the brain
Astrocytes
34
From which material the astrocyte creates myelin
Cholesterol
35
Which Apolipoproteins is usually impaired in Alzheimer disease
ApoE4
36
Which type of Apolipoproteins is usually increase in Alzheimer disease
APO E4