Dani Brain 2 Flashcards Preview

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Flashcards in Dani Brain 2 Deck (36)
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1
Q

How much of our brain is fat

A

60%

2
Q

How myelin allowed development of brain in vertebrates

A

Conducting nerves faster and decrease in size of nerves

3
Q

Which glial cell produces myelin sheet

A

Oligodendrocyte

4
Q

What does the myelin consist off

A

80% of fat and 20% protein

5
Q

Which types of protein are Present in the myalin

A

Proteolipid protein
Myelin basic protein
Myelin oligodendrocyte glycoprotein

6
Q

Does young children has Myelin

A

No

7
Q

Which type of cells generates myalin

A

Oligodendrocytes and Schwann cells

8
Q

How many axons does the Schwann cell can cover

A

1

9
Q

How many neurons each oligodendrocyte cover

A

Up to 50 exons

10
Q

When the myelination process is complete, is there a possibility of production new myelin?

A

Yes. Through learning new tasks

11
Q

In which area of the brain, the gray matter is located

A

In the outer part of the brain

12
Q

Which cells are considered part of the gray matter of the brain

A

Axons without myelin
Glial cells
capillary blood vessel
neutrophils

13
Q

Which type of cells the white matter contained

A

Oligodendrocytes and strocytes

14
Q

Which type of matter in the brain consist Myelinated cells

A

White matter

15
Q

What does the oligodendrocyte consume as an energy source

A

Glucose and lactate

16
Q

Which product can the oligodendrocyte send

A

Lactate

17
Q

To witch sub groups we split the myelin related diseases

A

Loss of myelin and defects in the development of them myelin

18
Q

Which types of diseases caused due to the Myelination

A

Multiple sclerosis

Gillian beret syndrome

19
Q

What ae the Dysmyelination dieseas

A

Pelizaeus merzbacher Disease
Cannavan disease
Schizophrenia

20
Q

Which nervous system multiple sclerosis is related to

A

Central nervous system (CNS)

21
Q

Which part of the brain cell is damaged during MS

A

Myelin

22
Q

Which gender suffers more from multiple sclerosis

A

Woman

23
Q

In which race MS is more common

A

Caucasians

24
Q

Which groups of fatty acid are present in the brain

A

Sphingolipids
Phospholipid
Cholesterol

25
Q

What does the fatty acid function for

A

Signaling molecules sources of energy

synaptogenesis neurogenesis impulse condition and other

26
Q

What is the main usage of lipids for the brain

A

Utilize acylated lipids to generate phospholipids for cell membrane

27
Q

How leptin affect energy expenditure in the brain

A

Increase it

28
Q

How leptin increases the energy expenditure in the brain

A

Buy acting on hypothalamic centers that increases fatty acids flow

29
Q

How much of the body cholesterol is located in the brain

A

I’m about to 25%

30
Q

Where does the brain cholesterol is produced

A

In the brain because it cannot cross the brain blood barrier

31
Q

Which type of cholesterol can cross the blood brain barrier

A

Very dense HDL

32
Q

Which regulatory element binding protein regulates the production cholesterol

A

SREBP2

33
Q

Which neural cells is the main producer of cholesterol in the brain

A

Astrocytes

34
Q

From which material the astrocyte creates myelin

A

Cholesterol

35
Q

Which Apolipoproteins is usually impaired in Alzheimer disease

A

ApoE4

36
Q

Which type of Apolipoproteins is usually increase in Alzheimer disease

A

APO E4