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Metabolism and Pathology > Integration Of Metabolism > Flashcards

Integration Of Metabolism Flashcards

1
Q

Which functions needs to be done by the liver in case of a diet rich in protein?

A

Amino acid catabolism
gluconeogenesis
glycogen breakdown

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2
Q

What functions needs to be done by the I’ver in case of a diet rich in carbohydrates?

A

Glycolysis , lipids synthesis , glycogen synthesis

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3
Q

What is the main source of the muscle when we perform light activity or rest?

A

Fatty acids
ketone bodies
And blood glucose

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4
Q

In case of light activity, which hormone is secreted?

A

Adrenalin

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5
Q

Which glut is activated in case of light activity?

A

Glut 4

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6
Q

Does the activation of glut 4 is sugar level dependent?

A

Yes

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7
Q

If there is low level of sugar, Will sugar enter the cells?

A

No

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8
Q

Why physical activity is good for diabetes

A

It helps insert sugar to the cells

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9
Q

How does adrenaline influence levels of calcium?

A

Levels goes up

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10
Q

Which mineral accumulate in case of increased adrenaline?

A

Calcium

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11
Q

Which enzymes AMP activates in the liver

A

Enzymes that break down glycogen

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12
Q

In case of intense activity, what is the primary source of energy?

A

Lactate

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13
Q

Does the body need oxygen to turn lactate into energy?

A

No

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14
Q

What gives us phosphocreatine ?

A

Energy

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15
Q

From which molecule we earn more energy,ATP or creatine phosphate?

A

Creatine phosphate

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16
Q

Why does the creatine yields high-level of energy?

A

The presence of two nitrogens

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17
Q

In which tissues glut 2 in mostly expressed?

A

Liver, pancreas, intestine

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18
Q

In which tissues glut 4 in mostly expressed?

A

Muscles, adipose, heart

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19
Q

How do we get energy from creatine?

A

Transfer its phosphate to ADP to get ATP

20
Q

What is the ratio between quantity of enrgy sources to their availability?

A

Contrast

21
Q

Does Slow switch fibers contain small amount of mitochondria?

A

No, it has a lot of them

22
Q

Which process fast switch is specializes at?

A

Lactic fermentation

23
Q

Marathon runners need more slow or fast switch fibers?

A

Slow swich

24
Q

Which enzyme is highly present in fast switch fiber muscles?

A

Lactate dehydrogenase

25
Q

In which state the glucose Alanin occurs?

A

Starvation

26
Q

During Cori cycle, which metabolic process is been stressed in the muscle?

A

Glycolysis

27
Q

Which product lS sent out from the muscle to the liver during Cori cycle?

A

Lactate

28
Q

Which product is sent out from the liver to the muscle during Cori cycle?

A

Glucose

29
Q

Why do we want to turn pyruvate to lactate during glycolysis?

A

To earn nad+

30
Q

How turning pyruvate to lactate helps us to do glycolysis?

A

Because we get more nad+ who is essential for step 6 of glycolysis

31
Q

In case of starvation, who is the first that we want give glucose to

A

Brain

32
Q

How can we utilize alpha keto acid?

A

Insert to krebs cycle, In the muscle or make acetyl CoA

33
Q

Which reaction alanine aminotrasterase catalyzes?

A

Glutamate transfer its amine to pyruvate to get alanine

34
Q

In wich tissue we are able to find a lot of alanine aminotransterase

A

In the muscle

35
Q

What is the end product of gluconeogenesis?

A

glucose

36
Q

What are the sources of pyruvate in gluconeogenesis?

A

Lactate and alanine from the muscle

37
Q

What are the sources of gluconeogenesis?

A

Lactate, alanine, glutamine, glycerol

38
Q

Can we get glucose from fatty acids

A

No

39
Q

To which product ketogenic amino acid break?

A

Acetyl CoA

40
Q

What is the major energy source of the liver

A

Fatty acids

41
Q

How can we use acetyl coa

A

Energy (krebs cycle), ketone bodies, build fatty acids

42
Q

How many acetyl coa are there in the original of ketone bodies

A

2

43
Q

What is the by product of generating ketone bodies

A

Acetone

44
Q

Does Keto acyl transfer is present in the liver

A

No

45
Q

Which enzyme breaks down keto bodies and does not present in the liver

A

Beta ketoacyl coa transferase

Metabolism and Pathology (28 decks)

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