Eicosonoids

Question 1

What are eicosonoids?

Answer 1

Fatty acids with 20 Carbons

Question 2

How many double bonds does the archidonat has?

Answer 2

4

Question 3

Which fatty acid is placed in the center of each Eicosonoid

Answer 3

Archidonate

Question 4

How do we able to get archidonate?

Answer 4

לקבל ממזון צמחי את 
linoleate
ועליו, בתהליכי desaturation ו-
elongation להוסיף קשרים כפולים במיקומים 
שלפני פחמן 10 ,כך שבנוסף לקשרים הכפולים 
איתם המולקולה מגיעה מהמזון, נוספים שני 
קשרים

Question 5

Which fatty acid we eat to get archidonate?

Answer 5

Linoleate

Question 6

What is the first step in generating prostaglandins?

Answer 6

Generate the first prostaglandin pgh2

Question 7

Which type of enzyme synthesizes pgh2

Answer 7

Oxygenates

Question 8

What is the name of the enzyme that synthesizes PGH2

Answer 8

COX

Question 9

What molecule cox uses for its function?

Answer 9

oxygen O2

Question 10

Which cox is more constitutive?

Answer 10

Cox1

Question 11

Which cox usually expressed after external signal in specific cells?

Answer 11

Cox 2

Question 12

How do we prevent cox with aspirin?

Answer 12

Cox undergoes esterification

Question 13

Over which cox aspirin is more reactive?

Answer 13

Cox1

Question 14

Can aspirin react over cox 2?

Answer 14

Yes

Question 15

How Aspirin can become harmful what taking it for long time?

Answer 15

Narrowed blood vessels

Broke the equilibrium of salts and caused heart attacks