Important parameters semester 1 Flashcards
(108 cards)
1
Q
Body water content
A
0.6 x BW = 42L
2
Q
Blood volume
A
PV / (1 - HMC) = 5L
3
Q
Plasma volume
A
0.25 x ECF = 3.5L
4
Q
ECF volume
A
0.2 x BW = 14L
5
Q
ICF volume
A
0.4 x BW = 28L
6
Q
Interstitial fluid volume
A
0.75 x ECF = 10.5L
7
Q
Hematocrit
A
Males : 42 to 54 %
Females : 38 - 46 %
8
Q
Hemoglobin concentration
A
12g/dL or higher
9
Q
Blood plasma Na+ concentration
A
142mM
10
Q
Blood plasma K+ concentration
A
4.4mM
11
Q
Blood plasma Ca2+ concentrations
A
Total : 2.1-2.8mM
Free : 1.1-1.4mM
12
Q
Blood plasma Cl- concentration
A
102mM
13
Q
Blood plasma HCO3- concentration
A
2.5mM
14
Q
Blood plasma protein concentration
A
1mM
15
Q
Intracellular Na+ concentration
A
15mM
16
Q
Extracellular Na+ concentration
A
135-147mM
17
Q
Intracellular K+ concentration
A
120mM
18
Q
Cytosolic Ca2+ concentration
A
100nM
19
Q
Intracellular Cl- concentration
A
20mM
20
Q
Intracellular HCO3- concentration
A
12-16mM
21
Q
Blood plasma osmolarity and oncotic pressure
A
290mOsm/L and 28mmHg
22
Q
Resting membrane potential of skeletal muscle cells
A
-90mV
23
Q
Equilibrium potential of Na+ in neurons
A
+60mV
24
Q
Equilibrium potential of K+ in neurons
A
-90mV
25
Equilibrium potential of Ca2+ in neurons
130mV
26
Equilibrium potential of Cl- in neurons
-70mV
27
Resting membrane potential of neurons
Around -70mV but changes depending on neuron
28
Duration of QRS coomplex of ECG
0.06 - 0.1s
29
Duration of P wave of ECG
0.08 - 0.1s
30
Duration of PQ (PR) interval
0.1 - 0.2s
31
Amplitude of R and T wave in ECG II lead
R: 0,4-1,3 mV
T: 0,1-0,6 mV
32
Stroke volume
EDV-ESV = 80mL
33
Amplitude of ST segment of ECG
supposed to be isoelectric (flat) so 0-1mV
34
Duration of cardiac cycle (HR = 75/min)
T = 60 / HR = 0.8 seconds (would be 1 if HR = 60)
35
Duration of systole (HR = 75/min)
0.27 seconds
36
Duration of diastole (HR = 75/min)
0.53 seconds
37
Systolic pressure in the aorta
120 mmHg
38
Diastolic pressure in the aorta
80 mmHg
39
Systolic pressure in the right ventricle
Less than 25 mmHg
40
Diastolic pressure in the right ventricle
Less than 5 mmHg
41
Systolic pressure in the left ventricle
About 110-120 mmHg
42
Diastolic pressure in the left ventricle
Low : about 5-10 mmHg
43
Systolic pressure in the pulmonary artery
Around 25 mmHg
44
Diastolic pressure in the pulmonary artery
Around 10 mmHg
45
Central venous pressure (BP in the vena cavae)
0-5 mmHg
46
Blood flow to skeletal muscle (during exercise too)
About 20% of the cardiac output so 1L/min, and 20L/min during max exercise
47
Blood flow to splanchnic area at rest and at max exercise
25% of CO so 1,25L/min at rest
| 700mL/min at exercise
48
Blood flow of heart
Coronary circulation is about 5% of the CO so 250mL/min
49
Renal blood flow
1200-1300 mL/min
50
Cerebrospinal fluid volume (/day, /hour, in general)
500mL produced / day, 25mL / hour
| In general there is only 15-150mL present
51
Protein concentration of CSF
nearly protein free
52
Blood flow of brain
15-20% of CO so 850mL/min
53
Blood flow of skin
2% of CO so 100mL/min
54
Hydrostatic capillary pressure in arteriolar end and venular end
+32mmHg at arterial end
| +25mmHg at venous end
55
Oxygen consumption in 1 minute
Approximately 250mL/min
56
Residual volume M and F
M : 1200 mL
| F : 1000 mL
57
Expiratory reserve volume M and F
M : 1200 mL
| F : 800 mL
58
Inspiratory reserve volume M and F
M : 3100 mL
| F : 1900 mL
59
Tidal volume
500mL
60
Vital capacity M and F
M : 4800 mL
| F : 3200 mL
61
Total lung capacity M and F
M : 6000 mL
| F : 4200 mL
62
Functional residual capacity
M : 2400 mL
| F : 1800 mL
63
Anatomical deadspace
volume of gas in the conducting system : 150mL
64
Alveolar deadspace
volume of the alveoli that is ventilated but not perfused : 0mL in physio conditions
65
Physiological deadspace
Anatomical + alveolar = 150mL
66
Alveolar ventilation
VA = (VCO2 * 863mmHg)/(PaCO2), around 4000mL/min
67
AVDO2 in the kidney
15mL O2/L
68
AVDO2 in the splanchnic area
30-40mL O2/L
69
AVDO2 in the brain
60mL O2/L
70
AVDO2 in the heart in resting condition and during exercise
rest: 110 ml O2/L (60-80% is extracted)
| for exercise: increase = increase in blood flow, extraction already at max
71
AVDO2 in the skeletal muscle in resting condition and during physical exercise
60mL O2/L at rest
| 150mL O2/L during exercise
72
Conduction velocity of different type of nerves
A-alpha (myelinated): 80-120 m/s
A-beta (myelinated): 40-70 m/s
B: (myelinated) 5-20 m/s
C (non-myelinated): 0,5-2 m/s
73
Duration of ventricular ejection (HR = 75/min)
0,25s
74
Duration of ventricular filling (HR = 75/min)
0,44s
75
Effective filtration pressure of capillaries in the arteriolar end and in the venular end
Artery : +15mmHg
| Venous : -9mmHg
76
AVDO2 in the systemic circulation
50mL 02/L
77
Intrapleural pressure and alveolar pressure during inspiration
Intrapleural pressure= -7 to -4 mmHg
| alveolar pressure= -0,7-0 mmHg
78
Intrapleural pressure and alveolar pressure during expiration
Intrapleural pressure= -7 to -4mmHg
| alveolar pressure= -0,7-0 mmHg
79
Intrapleural pressure and alveolar pressure at the end of inspiration
Intrapleural pressure= -7 mmHg
| alveolar pressure= 0 mmHg
80
Intrapleural pressure and alveolar pressure at the end of expiration
Intrapleural pressure= -4 mmHg
| alveolar pressure= 0 mmHg
81
PO2 and PCO2 of the alveolar gas
PO2 : 100mmHg
| PCO2 : 40mmHg
82
PO2 and PCO2 in the arteries
PO2 : 95mmHg
| PCO2 : 40mmHg
83
PO2 and PCO2 in the veins
PO2 : 40mmHg
| PCO2 : 46mmHg
84
Concentration of O2 in the arteries
200ml O2/L (97% saturation)
85
Concentration of O2 in the veins
150ml O2/L (75% saturation)
86
CO2 production in resting condition
210mL/min
87
Renal plasma flow
600-700mL/min
88
Glomerular filtration rate
120mL/min
89
Filtration fraction (kidney)
20%
90
Hydrostatic pressure in AFFERENT glomerular capillaries
53mmHg
91
Colloid osmotic pressure in AFFERENT glomerular capillaries
25mmHg
92
Hydrostatic pressure in EFFERENT glomerular capillaries
51mmHg
93
Colloid osmotic pressure in EFFERENT glomerular capillaries
33mmHg
94
Hydrostatic pressure in Bowman's space
12mmHg (afferent and efferent)
95
Colloid osmotic pressure in Bowman's space
0mmHg (afferent and efferent)
96
Effective filtration pressure in the glomerular afferent and efferent capillaries
Afferent : 15mmHg
| Efferent : 6mmHg
97
Urine volume (maximal concentration)
0,5L/day
98
Urine osmolarity (maximal concentration)
1200mOsm/L
99
Urine volume (max dilution)
15-20L/day
100
Urine osmolarity (max dilution)
30-50mOsm/L
101
Osmotic concentration and pressure in the proximal tubule
290mOsm and 300mmHg
102
Osmotic concentration and pressure in the interstitium in the cortex
290mOsm and 300mmHg
103
Transport maximum of tubular glucose-reabsorbtion
375mg/min 11mM
104
Buffer base
44-49 mEq/L
105
Arterial blood pH
7.35-7.45
106
Base excess
Around 0 mEq/L
107
Standard HCO3-
24mmol/L
108
Actual HCO3-
24mmol/L
