Flashcards in Infection Deck (188)
A young patient presents with a large number of persistent bacterial skin abscesses, what primary immunodeficiencies may he have? What tests would you like?
T cell deficiency
FBC, lymphocyte subset analysis, adhesion molecule expression, neutrophil function tests, IgG levels
What can cause primary immunodeficiencies?
Single gene disorders
What two general categories of secondary immunodeficiency are there? Examples?
Decreased production of immune component
- HIV, splenectomy, liver disease, malnutrition
Increased loss of immune components
- nephropathy, burns, enteropathy
What drugs can cause neutropenia?
Pheytoin, alcohol, chemotherapy, immunosuppressants
What diseases can cause neutropenia?
HIV, EBV, HBV, vit b deficiency, bone marrow cancer
Why might the spleen need removing?
Immune haemolytic disease
What disease can cause splenic atrophy?